| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 19-Nov-05 | vs Murray St (78) | 79-75 | Won | 0.3186 | 0.3441 |
| 22-Nov-05 | vs Illinois St (185) | 76-59 | Won | -0.4733 | -0.0000 |
| 25-Nov-05 | vs Holy Cross (130) | 77-55 | Won | -0.1008 | -0.0000 |
| 29-Nov-05 | vs Dayton (159) | 66-75 | Lost | -0.3222 | -1.0000 |
| 03-Dec-05 | vs Memphis (4) | 81-91 | Lost | 1.3572 | -0.6172 |
| 10-Dec-05 | at Vanderbilt (60) | 92-83 | Won | 1.0833 | 1.0000 |
| 14-Dec-05 | vs Ohio U. (99) | 86-58 | Won | 0.1311 | 0.1567 |
| 17-Dec-05 | vs Tennessee Tech (148) | 105-62 | Won | -0.2227 | -0.0000 |
| 22-Dec-05 | vs Dayton (159) | 81-63 | Won | 0.0209 | 0.0465 |
| 23-Dec-05 | vs LSU (14) | 75-72 | Won | 1.4213 | 1.0000 |
| 28-Dec-05 | vs Miami OH (87) | 75-65 | Won | 0.2262 | 0.2518 |
| 30-Dec-05 | vs North Carolina A&T (322) | 105-69 | Won | -1.7355 | -0.0000 |
| 04-Jan-06 | vs DePaul (80) | 82-60 | Won | 0.2802 | 0.3058 |
| 07-Jan-06 | at Marquette (31) | 70-66 | Won | 1.4220 | 1.0000 |
| 09-Jan-06 | at Connecticut (2) | 59-70 | Lost | 2.3915 | 0.0000 |
| 14-Jan-06 | vs Syracuse (20) | 58-77 | Lost | 0.9313 | -1.0000 |
| 19-Jan-06 | at Xavier OH (67) | 71-73 | Lost | 1.0501 | -0.9243 |
| 22-Jan-06 | vs Rutgers (56) | 71-66 | Won | 0.4894 | 0.5150 |
| 25-Jan-06 | at Louisville (54) | 50-67 | Lost | 1.1989 | -0.7755 |
| 28-Jan-06 | at Georgetown DC (19) | 57-76 | Lost | 1.6631 | -0.3113 |
| 31-Jan-06 | vs South Florida (229) | 73-60 | Won | -0.7598 | -0.0000 |
| 04-Feb-06 | at West Virginia (26) | 57-66 | Lost | 1.5203 | -0.4542 |
| 06-Feb-06 | vs Louisville (54) | 74-68 | Won | 0.5128 | 0.5384 |
| 12-Feb-06 | at Pittsburgh (12) | 69-89 | Lost | 1.8202 | -0.1542 |
| 15-Feb-06 | at Syracuse (20) | 82-65 | Won | 1.6174 | 1.0000 |
| 17-Feb-06 | vs Providence RI (98) | 66-64 | Won | 0.1506 | 0.1762 |
| 23-Feb-06 | vs Villanova (3) | 72-74 | Lost | 1.5456 | -0.4288 |
| 28-Feb-06 | at Seton Hall (52) | 62-72 | Lost | 1.2006 | -0.7738 |
| 04-Mar-06 | vs West Virginia (26) | 78-75 | Won | 0.8342 | 0.8598 |
| 08-Mar-06 | vs Syracuse (20) | 73-74 | Lost | 1.2743 | -0.7001 |
A red opponent rating indicates modification according to home court advantage (0.3430).