| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 19-Nov-05 | vs St Peter's (138) | 82-71 | Won | -0.1487 | -0.0000 |
| 23-Nov-05 | vs Robert Morris PA (252) | 86-59 | Won | -0.9057 | -0.0000 |
| 26-Nov-05 | vs Maine (289) | 62-49 | Won | -1.1515 | -0.0000 |
| 29-Nov-05 | vs St Francis NY (287) | 79-58 | Won | -1.1211 | -0.0000 |
| 04-Dec-05 | vs Auburn (113) | 78-41 | Won | -0.0080 | -0.0000 |
| 07-Dec-05 | at Duquesne (316) | 71-60 | Won | -0.9392 | -0.0000 |
| 10-Dec-05 | vs Penn St (75) | 91-54 | Won | 0.3308 | -0.0000 |
| 17-Dec-05 | vs Vermont (237) | 63-52 | Won | -0.8106 | -0.0000 |
| 21-Dec-05 | vs Coppin St (279) | 77-51 | Won | -1.0762 | -0.0000 |
| 28-Dec-05 | at South Carolina (71) | 58-51 | Won | 1.0228 | 0.5456 |
| 31-Dec-05 | vs Wisconsin (28) | 73-64 | Won | 0.7890 | 0.3118 |
| 04-Jan-06 | vs Notre Dame (64) | 100-97 | Won | 0.3722 | -0.0000 |
| 12-Jan-06 | vs DePaul (80) | 73-65 | Won | 0.2802 | -0.0000 |
| 15-Jan-06 | at Louisville (54) | 61-57 | Won | 1.1989 | 0.7217 |
| 18-Jan-06 | at Rutgers (56) | 76-68 | Won | 1.1755 | 0.6983 |
| 21-Jan-06 | at St John's NY (123) | 50-55 | Lost | 0.6125 | -1.0000 |
| 23-Jan-06 | vs Syracuse (20) | 80-67 | Won | 0.9313 | 0.4541 |
| 28-Jan-06 | vs Marquette (31) | 77-71 | Won | 0.7360 | 0.2588 |
| 31-Jan-06 | at Connecticut (2) | 76-80 | Lost | 2.3915 | -0.0857 |
| 05-Feb-06 | at Georgetown DC (19) | 58-61 | Lost | 1.6631 | -0.8140 |
| 09-Feb-06 | vs West Virginia (26) | 57-53 | Won | 0.8342 | 0.3570 |
| 12-Feb-06 | vs Cincinnati (41) | 89-69 | Won | 0.6314 | 0.1542 |
| 15-Feb-06 | at Providence RI (98) | 85-77 | Won | 0.8367 | 0.3595 |
| 18-Feb-06 | at Marquette (31) | 82-84 | Lost | 1.4220 | -1.0000 |
| 25-Feb-06 | vs Providence RI (98) | 81-68 | Won | 0.1506 | -0.0000 |
| 27-Feb-06 | at West Virginia (26) | 62-67 | Lost | 1.5203 | -0.9569 |
| 03-Mar-06 | vs Seton Hall (52) | 61-65 | Lost | 0.5145 | -1.0000 |
| 08-Mar-06 | vs Louisville (54) | 61-56 | Won | 0.8559 | 0.3787 |
| 09-Mar-06 | at West Virginia (26) | 68-57 | Won | 1.1772 | 0.7000 |
| 10-Mar-06 | at Villanova (3) | 68-54 | Won | 1.8886 | 1.0000 |
| 11-Mar-06 | vs Syracuse (20) | 61-65 | Lost | 1.2743 | -1.0000 |
A red opponent rating indicates modification according to home court advantage (0.3430).