| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 19-Nov-05 | vs Tennessee-Martin (207) | 78-61 | Won | -0.6372 | -0.0000 |
| 03-Dec-05 | vs Prairie View A&M (332) | 90-65 | Won | -2.3993 | -0.0000 |
| 04-Dec-05 | vs Arkansas St (209) | 67-55 | Won | -0.6601 | -0.0000 |
| 05-Dec-05 | vs Richmond (176) | 53-45 | Won | -0.4312 | -0.0000 |
| 10-Dec-05 | vs Akron (81) | 111-85 | Won | 0.2756 | 0.4198 |
| 13-Dec-05 | vs Chicago St (226) | 78-54 | Won | -0.7481 | -0.0000 |
| 17-Dec-05 | at Kentucky (35) | 61-73 | Lost | 1.3910 | -0.4649 |
| 20-Dec-05 | vs Middle Tennessee St (128) | 76-68 | Won | -0.0870 | 0.0571 |
| 21-Dec-05 | vs Coll of Charleston (187) | 78-63 | Won | -0.4932 | -0.0000 |
| 24-Dec-05 | vs Detroit Mercy (152) | 56-48 | Won | -0.2758 | -0.0000 |
| 28-Dec-05 | vs Fairleigh Dickinson (170) | 89-66 | Won | -0.3942 | -0.0000 |
| 31-Dec-05 | at Miami FL (76) | 58-43 | Won | 0.6687 | 0.8128 |
| 05-Jan-06 | vs Villanova (3) | 67-76 | Lost | 1.5456 | -0.3103 |
| 07-Jan-06 | at Providence RI (98) | 72-67 | Won | 0.8367 | 0.9808 |
| 09-Jan-06 | vs UC-Davis (299) | 81-58 | Won | -1.3363 | -0.0000 |
| 15-Jan-06 | vs Pittsburgh (12) | 57-61 | Lost | 1.1341 | -0.7217 |
| 17-Jan-06 | at St John's NY (123) | 56-68 | Lost | 0.6125 | -1.0000 |
| 21-Jan-06 | vs Connecticut (2) | 58-71 | Lost | 1.7054 | -0.1504 |
| 25-Jan-06 | vs Cincinnati (41) | 67-50 | Won | 0.6314 | 0.7755 |
| 28-Jan-06 | at Rutgers (56) | 56-65 | Lost | 1.1755 | -0.6804 |
| 30-Jan-06 | at Villanova (3) | 73-79 | Lost | 2.2317 | 0.0000 |
| 04-Feb-06 | vs Notre Dame (64) | 89-86 | Won | 0.3722 | 0.5164 |
| 06-Feb-06 | at Cincinnati (41) | 68-74 | Lost | 1.3175 | -0.5384 |
| 11-Feb-06 | vs South Florida (229) | 57-54 | Won | -0.7598 | -0.0000 |
| 18-Feb-06 | at Syracuse (20) | 66-79 | Lost | 1.6174 | -0.2385 |
| 22-Feb-06 | vs DePaul (80) | 65-53 | Won | 0.2802 | 0.4244 |
| 25-Feb-06 | at West Virginia (26) | 64-68 | Lost | 1.5203 | -0.3356 |
| 01-Mar-06 | vs Marquette (31) | 67-60 | Won | 0.7360 | 0.8801 |
| 04-Mar-06 | at Connecticut (2) | 80-84 | Lost | 2.3915 | 0.0000 |
| 08-Mar-06 | at Pittsburgh (12) | 56-61 | Lost | 1.4772 | -0.3787 |
A red opponent rating indicates modification according to home court advantage (0.3430).