| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 18-Nov-05 | vs Rice (215) | 82-65 | Won | -0.6846 | -0.0000 |
| 19-Nov-05 | vs Winthrop (86) | 64-71 | Lost | 0.2286 | -1.0000 |
| 23-Nov-05 | vs Eastern Washington (165) | 83-73 | Won | 0.0001 | -0.0000 |
| 25-Nov-05 | at Oral Roberts (144) | 73-70 | Won | 0.1720 | 0.0930 |
| 26-Nov-05 | vs South Carolina (71) | 92-89 | Won | 0.6797 | 0.6007 |
| 30-Nov-05 | at Nebraska (65) | 74-84 | Lost | 1.0535 | -1.0000 |
| 03-Dec-05 | vs South Dakota St (266) | 87-52 | Won | -1.0188 | -0.0000 |
| 07-Dec-05 | vs Valparaiso (193) | 69-54 | Won | -0.5397 | -0.0000 |
| 10-Dec-05 | at Wisconsin (28) | 63-77 | Lost | 1.4751 | -0.6039 |
| 17-Dec-05 | vs San Francisco (171) | 61-48 | Won | -0.4014 | -0.0000 |
| 19-Dec-05 | vs Oakland (260) | 90-69 | Won | -0.9771 | -0.0000 |
| 22-Dec-05 | vs Delaware St (167) | 60-48 | Won | -0.3690 | -0.0000 |
| 03-Jan-06 | vs Connecticut (2) | 94-79 | Won | 1.7054 | 1.0000 |
| 07-Jan-06 | vs Cincinnati (41) | 66-70 | Lost | 0.6314 | -1.0000 |
| 11-Jan-06 | at Seton Hall (52) | 67-63 | Won | 1.2006 | 1.0000 |
| 14-Jan-06 | at West Virginia (26) | 85-104 | Lost | 1.5203 | -0.5587 |
| 17-Jan-06 | at DePaul (80) | 82-79 | Won | 0.9663 | 0.8873 |
| 20-Jan-06 | vs Notre Dame (64) | 67-65 | Won | 0.3722 | 0.2932 |
| 25-Jan-06 | vs DePaul (80) | 62-47 | Won | 0.2802 | 0.2013 |
| 28-Jan-06 | at Pittsburgh (12) | 71-77 | Lost | 1.8202 | -0.2588 |
| 01-Feb-06 | vs St John's NY (123) | 81-61 | Won | -0.0736 | -0.0000 |
| 04-Feb-06 | at Villanova (3) | 67-72 | Lost | 2.2317 | 0.0000 |
| 12-Feb-06 | at Rutgers (56) | 84-91 | Lost | 1.1755 | -0.9035 |
| 16-Feb-06 | vs Georgetown DC (19) | 57-51 | Won | 0.9771 | 0.8981 |
| 18-Feb-06 | vs Pittsburgh (12) | 84-82 | Won | 1.1341 | 1.0000 |
| 25-Feb-06 | at Notre Dame (64) | 80-72 | Won | 1.0583 | 0.9793 |
| 01-Mar-06 | at Louisville (54) | 60-67 | Lost | 1.1989 | -0.8801 |
| 04-Mar-06 | vs Providence RI (98) | 88-78 | Won | 0.1506 | 0.0716 |
| 09-Mar-06 | vs Georgetown DC (19) | 59-62 | Lost | 1.3201 | -0.7589 |
A red opponent rating indicates modification according to home court advantage (0.3430).