| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 08-Nov-05 | vs Bethune-Cookman (275) | 68-37 | Won | -1.0677 | -0.0000 |
| 09-Nov-05 | vs Cornell NY (243) | 67-62 | Won | -0.8406 | -0.0000 |
| 17-Nov-05 | at Texas Tech (105) | 81-46 | Won | 0.4132 | 0.1388 |
| 18-Nov-05 | at Florida (9) | 70-75 | Lost | 1.5379 | -0.7364 |
| 22-Nov-05 | vs Bucknell (25) | 69-74 | Lost | 0.8558 | -1.0000 |
| 25-Nov-05 | vs Siena (139) | 96-77 | Won | -0.1510 | -0.0000 |
| 30-Nov-05 | vs Manhattan (90) | 87-82 | Won | 0.2087 | -0.0000 |
| 03-Dec-05 | vs TCU (262) | 80-64 | Won | -1.0020 | -0.0000 |
| 10-Dec-05 | vs Colgate (297) | 58-35 | Won | -1.2843 | -0.0000 |
| 18-Dec-05 | vs Davidson (117) | 90-80 | Won | -0.0352 | -0.0000 |
| 21-Dec-05 | vs Illinois-Chicago (133) | 75-61 | Won | -0.1072 | -0.0000 |
| 27-Dec-05 | at Towson (192) | 86-52 | Won | -0.1965 | -0.0000 |
| 30-Dec-05 | vs Kent St (53) | 78-66 | Won | 0.5137 | 0.2394 |
| 04-Jan-06 | vs UTEP (97) | 69-56 | Won | 0.1599 | -0.0000 |
| 08-Jan-06 | vs South Florida (229) | 63-57 | Won | -0.7598 | -0.0000 |
| 11-Jan-06 | at Notre Dame (64) | 88-82 | Won | 1.0583 | 0.7840 |
| 14-Jan-06 | at Cincinnati (41) | 77-58 | Won | 1.3175 | 1.0000 |
| 16-Jan-06 | vs Connecticut (2) | 80-88 | Lost | 1.7054 | -0.5689 |
| 21-Jan-06 | at Villanova (3) | 65-80 | Lost | 2.2317 | -0.0427 |
| 23-Jan-06 | at Pittsburgh (12) | 67-80 | Lost | 1.8202 | -0.4541 |
| 29-Jan-06 | vs Seton Hall (52) | 61-68 | Lost | 0.5145 | -1.0000 |
| 01-Feb-06 | vs Rutgers (56) | 86-84 | Won | 0.4894 | 0.2150 |
| 08-Feb-06 | at Connecticut (2) | 50-73 | Lost | 2.3915 | 0.0000 |
| 12-Feb-06 | at St John's NY (123) | 75-60 | Won | 0.6125 | 0.3381 |
| 15-Feb-06 | vs Cincinnati (41) | 65-82 | Lost | 0.6314 | -1.0000 |
| 18-Feb-06 | vs Louisville (54) | 79-66 | Won | 0.5128 | 0.2385 |
| 20-Feb-06 | vs West Virginia (26) | 60-58 | Won | 0.8342 | 0.5598 |
| 25-Feb-06 | at Georgetown DC (19) | 53-68 | Lost | 1.6631 | -0.6112 |
| 02-Mar-06 | at DePaul (80) | 69-108 | Lost | 0.9663 | -1.0000 |
| 05-Mar-06 | vs Villanova (3) | 82-92 | Lost | 1.5456 | -0.7288 |
| 08-Mar-06 | at Cincinnati (41) | 74-73 | Won | 0.9744 | 0.7001 |
| 09-Mar-06 | at Connecticut (2) | 86-84 | Won | 2.0484 | 1.0000 |
| 10-Mar-06 | at Georgetown DC (19) | 58-57 | Won | 1.3201 | 1.0000 |
| 11-Mar-06 | at Pittsburgh (12) | 65-61 | Won | 1.4772 | 1.0000 |
A red opponent rating indicates modification according to home court advantage (0.3430).