| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 10-Nov-05 | vs San José St (263) | 88-54 | Won | -1.0100 | -0.0000 |
| 11-Nov-05 | vs Georgia Southern (126) | 74-61 | Won | -0.0848 | 0.5021 |
| 17-Nov-05 | vs Syracuse (20) | 46-81 | Lost | 1.2743 | -0.1388 |
| 18-Nov-05 | at Wake Forest (70) | 73-78 | Lost | 0.6919 | -0.7213 |
| 23-Nov-05 | vs Furman (217) | 83-74 | Won | -0.6875 | -0.0000 |
| 26-Nov-05 | vs Morehead St (323) | 76-42 | Won | -1.7838 | -0.0000 |
| 30-Nov-05 | vs TCU (262) | 81-54 | Won | -1.0020 | -0.0000 |
| 03-Dec-05 | at San Francisco (171) | 72-90 | Lost | 0.2847 | -1.0000 |
| 07-Dec-05 | vs Louisiana Tech (91) | 53-68 | Lost | 0.2079 | -1.0000 |
| 10-Dec-05 | vs Texas-Pan American (328) | 103-50 | Won | -1.9478 | -0.0000 |
| 17-Dec-05 | at UNLV (106) | 73-84 | Lost | 0.7556 | -0.6576 |
| 21-Dec-05 | vs Arkansas (29) | 65-78 | Lost | 1.0911 | -0.3221 |
| 29-Dec-05 | at New Mexico St (120) | 69-63 | Won | 0.6262 | 1.0000 |
| 01-Jan-06 | vs UTEP (97) | 61-60 | Won | 0.1599 | 0.7468 |
| 07-Jan-06 | at Texas A&M (39) | 55-63 | Lost | 1.3586 | -0.0545 |
| 11-Jan-06 | vs Baylor (137) | 79-61 | Won | -0.1397 | 0.4472 |
| 14-Jan-06 | vs Iowa St (94) | 76-73 | Won | 0.1928 | 0.7797 |
| 17-Jan-06 | at Texas (8) | 46-80 | Lost | 1.8887 | 0.0000 |
| 21-Jan-06 | at Oklahoma (33) | 48-60 | Lost | 1.4075 | -0.0056 |
| 28-Jan-06 | vs Oklahoma St (89) | 92-90 | Won | 0.2145 | 0.8013 |
| 30-Jan-06 | at Kansas (17) | 52-86 | Lost | 1.7304 | 0.0000 |
| 04-Feb-06 | vs Missouri (141) | 73-55 | Won | -0.1554 | 0.4314 |
| 06-Feb-06 | vs Texas (8) | 44-65 | Lost | 1.2027 | -0.2105 |
| 11-Feb-06 | at Colorado (51) | 64-66 | Lost | 1.2018 | -0.2113 |
| 15-Feb-06 | vs Kansas St (116) | 70-56 | Won | -0.0342 | 0.5526 |
| 18-Feb-06 | at Nebraska (65) | 70-64 | Won | 1.0535 | 1.0000 |
| 20-Feb-06 | vs Oklahoma (33) | 70-71 | Lost | 0.7214 | -0.6917 |
| 25-Feb-06 | at Oklahoma St (89) | 63-74 | Lost | 0.9005 | -0.5126 |
| 01-Mar-06 | at Baylor (137) | 66-77 | Lost | 0.5464 | -0.8667 |
| 04-Mar-06 | vs Texas A&M (39) | 59-75 | Lost | 0.6726 | -0.7406 |
| 09-Mar-06 | vs Kansas St (116) | 73-65 | Won | 0.3088 | 0.8956 |
| 10-Mar-06 | at Texas (8) | 70-77 | Lost | 1.5457 | 0.0000 |
A red opponent rating indicates modification according to home court advantage (0.3430).