| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 10-Nov-05 | vs Mississippi Valley St (312) | 78-64 | Won | -1.5675 | -0.0000 |
| 11-Nov-05 | vs George Mason (49) | 83-78 | Won | 0.5392 | 0.8473 |
| 17-Nov-05 | vs Florida (9) | 72-77 | Lost | 1.5379 | -0.1539 |
| 18-Nov-05 | vs Texas Tech (105) | 78-73 | Won | 0.4132 | 0.7213 |
| 21-Nov-05 | vs UNC-Asheville (248) | 79-63 | Won | -0.8660 | -0.0000 |
| 25-Nov-05 | vs Appalachian St (223) | 91-78 | Won | -0.7268 | -0.0000 |
| 29-Nov-05 | vs Wisconsin (28) | 91-88 | Won | 0.7890 | 1.0000 |
| 03-Dec-05 | at Elon (179) | 78-59 | Won | -0.1065 | 0.2016 |
| 13-Dec-05 | vs DePaul (80) | 81-84 | Lost | 0.2802 | -1.0000 |
| 17-Dec-05 | vs Princeton (220) | 61-42 | Won | -0.6996 | -0.0000 |
| 22-Dec-05 | at Richmond (176) | 47-40 | Won | 0.2549 | 0.5630 |
| 30-Dec-05 | vs Charleston Southern (227) | 87-47 | Won | -0.7537 | -0.0000 |
| 03-Jan-06 | vs East Carolina (302) | 58-54 | Won | -1.3513 | -0.0000 |
| 08-Jan-06 | vs Duke (1) | 64-82 | Lost | 1.7812 | 0.0000 |
| 11-Jan-06 | at Clemson (59) | 73-74 | Lost | 1.1276 | -0.5643 |
| 15-Jan-06 | at Maryland (45) | 86-90 | Lost | 1.2623 | -0.4296 |
| 18-Jan-06 | vs Georgia Tech (122) | 86-71 | Won | -0.0644 | 0.2437 |
| 21-Jan-06 | at North Carolina St (22) | 82-92 | Lost | 1.5597 | -0.1322 |
| 24-Jan-06 | vs Florida St (36) | 68-75 | Lost | 0.7032 | -0.9887 |
| 28-Jan-06 | vs Virginia Tech (115) | 70-76 | Lost | -0.0173 | -1.0000 |
| 31-Jan-06 | at Miami FL (76) | 69-78 | Lost | 1.0117 | -0.6801 |
| 04-Feb-06 | at Virginia (66) | 73-75 | Lost | 1.0534 | -0.6384 |
| 08-Feb-06 | vs Boston College (16) | 66-72 | Lost | 1.0453 | -0.6466 |
| 11-Feb-06 | vs Charlotte (92) | 59-56 | Won | 0.2046 | 0.5127 |
| 14-Feb-06 | at Duke (1) | 70-93 | Lost | 2.4673 | 0.0000 |
| 19-Feb-06 | vs North Carolina (13) | 72-83 | Lost | 1.1254 | -0.5665 |
| 22-Feb-06 | vs Clemson (59) | 74-68 | Won | 0.4415 | 0.7496 |
| 25-Feb-06 | at Georgia Tech (122) | 61-76 | Lost | 0.6217 | -1.0000 |
| 28-Feb-06 | at Boston College (16) | 65-80 | Lost | 1.7314 | 0.0000 |
| 04-Mar-06 | vs North Carolina St (22) | 76-63 | Won | 0.8736 | 1.0000 |
| 09-Mar-06 | at Florida St (36) | 78-66 | Won | 1.0462 | 1.0000 |
| 10-Mar-06 | at North Carolina St (22) | 82-71 | Won | 1.2167 | 1.0000 |
| 11-Mar-06 | at Duke (1) | 66-78 | Lost | 2.1242 | 0.0000 |
A red opponent rating indicates modification according to home court advantage (0.3430).