| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 13-Nov-05 | at Coppin St (279) | 82-65 | Won | -0.7332 | -0.0000 |
| 14-Nov-05 | vs Northwestern (82) | 47-61 | Lost | 0.6131 | -0.9346 |
| 15-Nov-05 | at Wyoming (178) | 78-87 | Lost | 0.2377 | -1.0000 |
| 23-Nov-05 | vs Mississippi St (108) | 38-53 | Lost | 0.0642 | -1.0000 |
| 26-Nov-05 | at Georgia St (225) | 73-68 | Won | -0.0540 | 0.3983 |
| 28-Nov-05 | vs Portland (198) | 59-46 | Won | -0.5732 | -0.0000 |
| 30-Nov-05 | vs Davidson (117) | 85-81 | Won | -0.0352 | 0.4171 |
| 03-Dec-05 | at Louisiana-Lafayette (162) | 67-62 | Won | 0.3490 | 0.8013 |
| 10-Dec-05 | vs Valparaiso (193) | 77-80 | Lost | -0.5397 | -1.0000 |
| 19-Dec-05 | vs Indiana (24) | 54-71 | Lost | 0.8603 | -0.6874 |
| 22-Dec-05 | at Rutgers (56) | 85-82 | Won | 1.1755 | 1.0000 |
| 31-Dec-05 | vs UNC-Asheville (248) | 92-59 | Won | -0.8660 | -0.0000 |
| 04-Jan-06 | vs Rhode Island (142) | 88-80 | Won | -0.1639 | 0.2885 |
| 07-Jan-06 | at Dayton (159) | 73-65 | Won | 0.3639 | 0.8163 |
| 11-Jan-06 | at La Salle (100) | 64-52 | Won | 0.7970 | 1.0000 |
| 14-Jan-06 | vs Xavier OH (67) | 65-78 | Lost | 0.3641 | -1.0000 |
| 17-Jan-06 | at St Joseph's PA (55) | 57-50 | Won | 1.1916 | 1.0000 |
| 21-Jan-06 | vs George Washington (7) | 69-83 | Lost | 1.2530 | -0.2946 |
| 28-Jan-06 | at Richmond (176) | 56-63 | Lost | 0.2549 | -1.0000 |
| 01-Feb-06 | at St Bonaventure (242) | 76-60 | Won | -0.1523 | 0.3001 |
| 04-Feb-06 | vs Dayton (159) | 62-49 | Won | -0.3222 | 0.1302 |
| 08-Feb-06 | vs Temple (74) | 66-59 | Won | 0.3323 | 0.7847 |
| 11-Feb-06 | at Wake Forest (70) | 56-59 | Lost | 1.0349 | -0.5127 |
| 15-Feb-06 | vs Richmond (176) | 64-47 | Won | -0.4312 | 0.0212 |
| 18-Feb-06 | at Fordham (132) | 81-75 | Won | 0.5811 | 1.0000 |
| 22-Feb-06 | at Massachusetts (125) | 72-71 | Won | 0.6038 | 1.0000 |
| 25-Feb-06 | vs St Louis (103) | 74-77 | Lost | 0.0798 | -1.0000 |
| 01-Mar-06 | vs Duquesne (316) | 77-71 | Won | -1.6253 | -0.0000 |
| 04-Mar-06 | at George Washington (7) | 85-86 | Lost | 1.9391 | 0.0000 |
| 09-Mar-06 | at Xavier OH (67) | 55-59 | Lost | 1.0501 | -0.4975 |
A red opponent rating indicates modification according to home court advantage (0.3430).