| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 19-Nov-05 | vs Old Dominion (73) | 52-65 | Lost | 0.6758 | -0.5623 |
| 20-Nov-05 | vs Georgia (95) | 68-79 | Lost | 0.5277 | -0.7104 |
| 21-Nov-05 | vs Norfolk St (269) | 72-53 | Won | -0.7036 | 0.0583 |
| 26-Nov-05 | vs St Francis NY (287) | 60-66 | Lost | -1.1211 | -1.0000 |
| 28-Nov-05 | at Siena (139) | 54-64 | Lost | 0.5351 | -0.7030 |
| 01-Dec-05 | vs Iona (48) | 70-71 | Lost | 0.5473 | -0.6908 |
| 04-Dec-05 | at Holy Cross (130) | 63-71 | Lost | 0.5853 | -0.6528 |
| 07-Dec-05 | at Virginia (66) | 62-60 | Won | 1.0534 | 1.0000 |
| 14-Dec-05 | at Fairfield (206) | 95-80 | Won | 0.0560 | 0.8179 |
| 23-Dec-05 | at Manhattan (90) | 68-81 | Lost | 0.8948 | -0.3433 |
| 28-Dec-05 | at Notre Dame (64) | 49-85 | Lost | 1.0583 | -0.1798 |
| 31-Dec-05 | vs Lafayette (270) | 71-52 | Won | -1.0537 | -0.0000 |
| 04-Jan-06 | vs Dayton (159) | 66-56 | Won | -0.3222 | 0.4397 |
| 07-Jan-06 | at Rhode Island (142) | 59-64 | Lost | 0.5222 | -0.7159 |
| 09-Jan-06 | vs Pennsylvania (121) | 78-63 | Won | -0.0621 | 0.6998 |
| 15-Jan-06 | vs Duquesne (316) | 90-63 | Won | -1.6253 | -0.0000 |
| 18-Jan-06 | at Massachusetts (125) | 61-74 | Lost | 0.6038 | -0.6343 |
| 21-Jan-06 | vs St Bonaventure (242) | 79-72 | Won | -0.8384 | -0.0000 |
| 28-Jan-06 | at St Louis (103) | 54-64 | Lost | 0.7659 | -0.4722 |
| 01-Feb-06 | vs Richmond (176) | 63-45 | Won | -0.4312 | 0.3307 |
| 04-Feb-06 | at Duquesne (316) | 90-81 | Won | -0.9392 | -0.0000 |
| 09-Feb-06 | at St Bonaventure (242) | 81-70 | Won | -0.1523 | 0.6096 |
| 12-Feb-06 | vs Rhode Island (142) | 79-76 | Won | -0.1639 | 0.5980 |
| 15-Feb-06 | at Xavier OH (67) | 64-84 | Lost | 1.0501 | -0.1880 |
| 18-Feb-06 | vs Charlotte (92) | 75-81 | Lost | 0.2046 | -1.0000 |
| 22-Feb-06 | at St Joseph's PA (55) | 58-64 | Lost | 1.1916 | -0.0465 |
| 25-Feb-06 | vs George Washington (7) | 67-78 | Lost | 1.2530 | 0.0000 |
| 01-Mar-06 | vs La Salle (100) | 83-74 | Won | 0.1109 | 0.8728 |
| 05-Mar-06 | at Temple (74) | 69-52 | Won | 1.0184 | 1.0000 |
| 08-Mar-06 | vs Richmond (176) | 45-37 | Won | -0.0881 | 0.6738 |
| 09-Mar-06 | at La Salle (100) | 64-62 | Won | 0.4540 | 1.0000 |
| 10-Mar-06 | at Xavier OH (67) | 59-70 | Lost | 1.0501 | -0.1880 |
A red opponent rating indicates modification according to home court advantage (0.3430).