| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 18-Nov-05 | at Wisconsin (28) | 51-80 | Lost | 1.1321 | 0.0000 |
| 20-Nov-05 | at Eastern Kentucky (194) | 60-67 | Lost | -0.2026 | -0.4990 |
| 21-Nov-05 | at Fordham (132) | 53-72 | Lost | 0.2381 | -0.0583 |
| 26-Nov-05 | at George Washington (7) | 69-80 | Lost | 1.9391 | 0.0000 |
| 30-Nov-05 | vs Towson (192) | 78-49 | Won | -0.5395 | 1.0000 |
| 03-Dec-05 | at Hampton (274) | 57-43 | Won | -0.3804 | 1.0000 |
| 12-Dec-05 | at Ohio State (6) | 59-92 | Lost | 1.9835 | 0.0000 |
| 16-Dec-05 | at Central Florida (231) | 47-63 | Lost | -0.0777 | -0.3741 |
| 19-Dec-05 | at Fresno St (127) | 70-89 | Lost | 0.6011 | 0.0000 |
| 21-Dec-05 | at Creighton (46) | 47-63 | Lost | 1.2595 | 0.0000 |
| 27-Dec-05 | at Nevada (27) | 46-56 | Lost | 1.5146 | 0.0000 |
| 04-Jan-06 | at Florida A&M (265) | 64-76 | Lost | -0.3294 | -0.6258 |
| 07-Jan-06 | vs Howard (317) | 82-79 | Won | -1.6308 | 0.0729 |
| 09-Jan-06 | vs MD-Eastern Shore (318) | 74-62 | Won | -1.6511 | 0.0526 |
| 14-Jan-06 | at Coppin St (279) | 65-75 | Lost | -0.3901 | -0.6865 |
| 16-Jan-06 | at Morgan St (329) | 81-53 | Won | -1.3707 | 0.3329 |
| 23-Jan-06 | vs Delaware St (167) | 54-57 | Lost | -0.3690 | -0.6654 |
| 28-Jan-06 | vs North Carolina A&T (322) | 55-43 | Won | -1.7355 | -0.0000 |
| 30-Jan-06 | vs South Carolina St (233) | 44-56 | Lost | -0.7696 | -1.0000 |
| 04-Feb-06 | at Howard (317) | 65-64 | Won | -0.9447 | 0.7589 |
| 06-Feb-06 | at MD-Eastern Shore (318) | 67-59 | Won | -0.9650 | 0.7386 |
| 11-Feb-06 | vs Coppin St (279) | 54-58 | Lost | -1.0762 | -1.0000 |
| 13-Feb-06 | vs Morgan St (329) | 59-63 | Lost | -2.0568 | -1.0000 |
| 16-Feb-06 | vs Hampton (274) | 52-51 | Won | -1.0665 | 0.6372 |
| 20-Feb-06 | at Delaware St (167) | 50-59 | Lost | 0.3170 | 0.0000 |
| 25-Feb-06 | at North Carolina A&T (322) | 75-60 | Won | -1.0494 | 0.6543 |
| 27-Feb-06 | at South Carolina St (233) | 52-72 | Lost | -0.0835 | -0.3798 |
| 01-Mar-06 | vs Bethune-Cookman (275) | 80-66 | Won | -1.0677 | 0.6359 |
| 07-Mar-06 | vs MD-Eastern Shore (318) | 73-71 | Won | -1.3080 | 0.3956 |
| 08-Mar-06 | at Coppin St (279) | 79-67 | Won | -0.7332 | 0.9705 |
| 10-Mar-06 | at Hampton (274) | 56-73 | Lost | -0.7234 | -1.0000 |
A red opponent rating indicates modification according to home court advantage (0.3430).