| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 20-Nov-05 | vs Chicago St (226) | 81-52 | Won | -0.7481 | -0.0000 |
| 22-Nov-05 | vs Butler (96) | 79-69 | Won | 0.1817 | -0.0000 |
| 28-Nov-05 | vs Virginia Tech (115) | 69-56 | Won | -0.0173 | -0.0000 |
| 10-Dec-05 | at St Joseph's PA (55) | 81-74 | Won | 1.1916 | 0.5512 |
| 12-Dec-05 | vs Norfolk St (269) | 92-59 | Won | -1.0467 | -0.0000 |
| 14-Dec-05 | vs Belmont (196) | 85-75 | Won | -0.5630 | -0.0000 |
| 17-Dec-05 | at Iowa St (94) | 70-67 | Won | 0.5358 | -0.0000 |
| 23-Dec-05 | vs Tennessee St (199) | 74-65 | Won | -0.5828 | -0.0000 |
| 28-Dec-05 | vs Gardner-Webb (213) | 87-58 | Won | -0.6755 | -0.0000 |
| 31-Dec-05 | vs LSU (14) | 78-76 | Won | 1.0783 | 0.4378 |
| 05-Jan-06 | vs Penn St (75) | 104-69 | Won | 0.3308 | -0.0000 |
| 07-Jan-06 | at Indiana (24) | 79-81 | Lost | 1.5464 | -1.0000 |
| 11-Jan-06 | at Purdue (143) | 80-64 | Won | 0.5174 | -0.0000 |
| 15-Jan-06 | vs Michigan St (21) | 59-62 | Lost | 0.8756 | -1.0000 |
| 18-Jan-06 | vs Wisconsin (28) | 77-67 | Won | 0.7890 | 0.1486 |
| 21-Jan-06 | at Penn St (75) | 75-64 | Won | 1.0168 | 0.3764 |
| 28-Jan-06 | at Iowa (10) | 62-67 | Lost | 1.8440 | -0.7965 |
| 30-Jan-06 | vs Florida A&M (265) | 95-53 | Won | -1.0155 | -0.0000 |
| 04-Feb-06 | vs Minnesota (68) | 67-53 | Won | 0.3640 | -0.0000 |
| 09-Feb-06 | at Michigan (30) | 94-85 | Won | 1.4252 | 0.7847 |
| 12-Feb-06 | vs Illinois (5) | 69-53 | Won | 1.2985 | 0.6581 |
| 15-Feb-06 | at Wisconsin (28) | 73-78 | Lost | 1.4751 | -1.0000 |
| 18-Feb-06 | vs Northwestern (82) | 61-52 | Won | 0.2700 | -0.0000 |
| 22-Feb-06 | at Michigan St (21) | 79-68 | Won | 1.5617 | 0.9212 |
| 25-Feb-06 | vs Michigan (30) | 64-54 | Won | 0.7391 | 0.0987 |
| 01-Mar-06 | at Northwestern (82) | 56-53 | Won | 0.9561 | 0.3157 |
| 05-Mar-06 | vs Purdue (143) | 76-57 | Won | -0.1687 | -0.0000 |
| 10-Mar-06 | vs Penn St (75) | 63-56 | Won | 0.6738 | 0.0334 |
| 11-Mar-06 | at Indiana (24) | 52-51 | Won | 1.2033 | 0.5629 |
| 12-Mar-06 | vs Iowa (10) | 60-67 | Lost | 1.5009 | -1.0000 |
A red opponent rating indicates modification according to home court advantage (0.3430).