| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 18-Nov-05 | vs South Dakota St (266) | 90-65 | Won | -1.0188 | -0.0000 |
| 20-Nov-05 | vs Texas-Pan American (328) | 71-59 | Won | -1.9478 | -0.0000 |
| 22-Nov-05 | vs Texas Southern (325) | 93-59 | Won | -1.8704 | -0.0000 |
| 25-Nov-05 | vs Wichita St (34) | 55-54 | Won | 1.0544 | 0.4128 |
| 26-Nov-05 | vs Rutgers (56) | 77-57 | Won | 0.8324 | 0.1909 |
| 29-Nov-05 | at North Carolina (13) | 68-64 | Won | 1.8115 | 1.0000 |
| 03-Dec-05 | vs Xavier OH (67) | 65-62 | Won | 0.7071 | 0.0655 |
| 05-Dec-05 | vs Arkansas-Little Rock (200) | 75-49 | Won | -0.5832 | -0.0000 |
| 08-Dec-05 | vs Georgetown DC (19) | 58-48 | Won | 0.9771 | 0.3355 |
| 10-Dec-05 | at Oregon (119) | 89-59 | Won | 0.3059 | -0.0000 |
| 18-Dec-05 | vs Coppin St (279) | 61-42 | Won | -1.0762 | -0.0000 |
| 21-Dec-05 | vs Missouri (141) | 82-50 | Won | 0.1876 | -0.0000 |
| 28-Dec-05 | vs SE Missouri St (313) | 89-64 | Won | -1.5691 | -0.0000 |
| 30-Dec-05 | vs Tennessee-Martin (207) | 84-46 | Won | -0.6372 | -0.0000 |
| 05-Jan-06 | vs Michigan St (21) | 60-50 | Won | 0.8756 | 0.2340 |
| 07-Jan-06 | at Iowa (10) | 48-63 | Lost | 1.8440 | -0.7976 |
| 14-Jan-06 | vs Michigan (30) | 79-74 | Won | 0.7391 | 0.0975 |
| 17-Jan-06 | at Indiana (24) | 60-62 | Lost | 1.5464 | -1.0000 |
| 21-Jan-06 | at Northwestern (82) | 58-47 | Won | 0.9561 | 0.3145 |
| 25-Jan-06 | vs Minnesota (68) | 77-53 | Won | 0.3640 | -0.0000 |
| 28-Jan-06 | vs Purdue (143) | 76-58 | Won | -0.1687 | -0.0000 |
| 31-Jan-06 | at Wisconsin (28) | 66-51 | Won | 1.4751 | 0.8335 |
| 04-Feb-06 | vs Penn St (75) | 65-66 | Lost | 0.3308 | -1.0000 |
| 12-Feb-06 | at Ohio State (6) | 53-69 | Lost | 1.9835 | -0.6581 |
| 15-Feb-06 | vs Northwestern (82) | 63-47 | Won | 0.2700 | -0.0000 |
| 19-Feb-06 | vs Indiana (24) | 70-58 | Won | 0.8603 | 0.2187 |
| 21-Feb-06 | at Michigan (30) | 64-72 | Lost | 1.4252 | -1.0000 |
| 25-Feb-06 | vs Iowa (10) | 71-59 | Won | 1.1579 | 0.5163 |
| 28-Feb-06 | at Minnesota (68) | 71-65 | Won | 1.0501 | 0.4085 |
| 04-Mar-06 | at Michigan St (21) | 75-68 | Won | 1.5617 | 0.9201 |
| 10-Mar-06 | vs Michigan St (21) | 56-61 | Lost | 1.2186 | -1.0000 |
A red opponent rating indicates modification according to home court advantage (0.3430).