| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 19-Nov-05 | vs Cornell NY (243) | 66-54 | Won | -0.8406 | -0.0000 |
| 23-Nov-05 | vs Nicholls St (282) | 93-56 | Won | -1.0998 | -0.0000 |
| 26-Nov-05 | vs LIU-Brooklyn (285) | 80-64 | Won | -1.1104 | -0.0000 |
| 29-Nov-05 | vs Clemson (59) | 88-96 | Lost | 0.4415 | -1.0000 |
| 03-Dec-05 | at Texas A&M (39) | 55-60 | Lost | 1.3586 | -0.3152 |
| 07-Dec-05 | vs UMKC (238) | 75-71 | Won | -0.8112 | -0.0000 |
| 10-Dec-05 | at Pittsburgh (12) | 54-91 | Lost | 1.8202 | 0.0000 |
| 18-Dec-05 | vs St Francis PA (327) | 88-74 | Won | -1.9277 | -0.0000 |
| 20-Dec-05 | vs New Hampshire (276) | 75-51 | Won | -1.0683 | -0.0000 |
| 28-Dec-05 | vs IPFW (272) | 74-59 | Won | -1.0629 | -0.0000 |
| 31-Dec-05 | vs Mt St Mary's MD (253) | 65-53 | Won | -0.9114 | -0.0000 |
| 05-Jan-06 | at Ohio State (6) | 69-104 | Lost | 1.9835 | 0.0000 |
| 11-Jan-06 | at Northwestern (82) | 65-61 | Won | 0.9561 | 1.0000 |
| 14-Jan-06 | vs Iowa (10) | 76-80 | Lost | 1.1579 | -0.5159 |
| 18-Jan-06 | vs Purdue (143) | 74-54 | Won | -0.1687 | 0.1575 |
| 21-Jan-06 | vs Ohio State (6) | 64-75 | Lost | 1.2974 | -0.3764 |
| 25-Jan-06 | at Wisconsin (28) | 43-72 | Lost | 1.4751 | -0.1987 |
| 28-Jan-06 | at Michigan St (21) | 60-69 | Lost | 1.5617 | -0.1121 |
| 01-Feb-06 | vs Michigan (30) | 65-71 | Lost | 0.7391 | -0.9347 |
| 04-Feb-06 | at Illinois (5) | 66-65 | Won | 1.9846 | 1.0000 |
| 08-Feb-06 | vs Minnesota (68) | 66-77 | Lost | 0.3640 | -1.0000 |
| 11-Feb-06 | vs Wisconsin (28) | 62-82 | Lost | 0.7890 | -0.8848 |
| 15-Feb-06 | vs Indiana (24) | 71-68 | Won | 0.8603 | 1.0000 |
| 18-Feb-06 | at Purdue (143) | 69-61 | Won | 0.5174 | 0.8436 |
| 22-Feb-06 | at Indiana (24) | 65-69 | Lost | 1.5464 | -0.1275 |
| 25-Feb-06 | vs Northwestern (82) | 68-55 | Won | 0.2700 | 0.5962 |
| 01-Mar-06 | at Iowa (10) | 38-65 | Lost | 1.8440 | 0.0000 |
| 09-Mar-06 | vs Northwestern (82) | 60-42 | Won | 0.6131 | 0.9393 |
| 10-Mar-06 | at Ohio State (6) | 56-63 | Lost | 1.6404 | -0.0334 |
A red opponent rating indicates modification according to home court advantage (0.3430).