| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 13-Nov-05 | at Lehigh (172) | 61-59 | Won | -0.0592 | 0.3277 |
| 14-Nov-05 | at Charlotte (92) | 61-47 | Won | 0.5477 | 0.9346 |
| 15-Nov-05 | vs UNC-Wilmington (40) | 48-56 | Lost | 0.9960 | -0.6170 |
| 21-Nov-05 | vs Florida Atlantic (264) | 69-59 | Won | -1.0116 | -0.0000 |
| 26-Nov-05 | at DePaul (80) | 49-59 | Lost | 0.9663 | -0.6467 |
| 30-Nov-05 | at Virginia (66) | 57-72 | Lost | 1.0534 | -0.5596 |
| 03-Dec-05 | vs Delaware St (167) | 61-54 | Won | -0.3690 | 0.0179 |
| 14-Dec-05 | vs Illinois-Chicago (133) | 62-71 | Lost | -0.1072 | -1.0000 |
| 18-Dec-05 | at Seton Hall (52) | 44-42 | Won | 1.2006 | 1.0000 |
| 01-Jan-06 | vs Northern Colorado (320) | 82-47 | Won | -1.7337 | -0.0000 |
| 04-Jan-06 | vs Purdue (143) | 66-53 | Won | -0.1687 | 0.2182 |
| 07-Jan-06 | at Minnesota (68) | 57-49 | Won | 1.0501 | 1.0000 |
| 11-Jan-06 | vs Penn St (75) | 61-65 | Lost | 0.3308 | -1.0000 |
| 14-Jan-06 | at Wisconsin (28) | 52-68 | Lost | 1.4751 | -0.1380 |
| 18-Jan-06 | at Michigan (30) | 51-68 | Lost | 1.4252 | -0.1879 |
| 21-Jan-06 | vs Illinois (5) | 47-58 | Lost | 1.2985 | -0.3145 |
| 25-Jan-06 | at Purdue (143) | 78-76 | Won | 0.5174 | 0.9043 |
| 01-Feb-06 | at Indiana (24) | 63-72 | Lost | 1.5464 | -0.0667 |
| 04-Feb-06 | vs Michigan St (21) | 66-77 | Lost | 0.8756 | -0.7375 |
| 08-Feb-06 | vs Iowa (10) | 51-48 | Won | 1.1579 | 1.0000 |
| 11-Feb-06 | vs IPFW (272) | 73-49 | Won | -1.0629 | -0.0000 |
| 15-Feb-06 | at Illinois (5) | 47-63 | Lost | 1.9846 | 0.0000 |
| 18-Feb-06 | at Ohio State (6) | 52-61 | Lost | 1.9835 | 0.0000 |
| 23-Feb-06 | vs Wisconsin (28) | 62-51 | Won | 0.7890 | 1.0000 |
| 25-Feb-06 | at Penn St (75) | 55-68 | Lost | 1.0168 | -0.5962 |
| 01-Mar-06 | vs Ohio State (6) | 53-56 | Lost | 1.2974 | -0.3157 |
| 04-Mar-06 | vs Minnesota (68) | 57-53 | Won | 0.3640 | 0.7509 |
| 09-Mar-06 | at Penn St (75) | 42-60 | Lost | 0.6738 | -0.9393 |
A red opponent rating indicates modification according to home court advantage (0.3430).