| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 19-Nov-05 | vs Gardner-Webb (213) | 83-80 | Won | -0.6755 | -0.0000 |
| 22-Nov-05 | vs Cleveland St (244) | 112-55 | Won | -0.8421 | -0.0000 |
| 25-Nov-05 | vs UC-Santa Barbara (191) | 83-66 | Won | -0.5225 | -0.0000 |
| 29-Nov-05 | vs Illinois (5) | 64-68 | Lost | 1.2985 | -1.0000 |
| 03-Dec-05 | at Kentucky (35) | 83-79 | Won | 1.3910 | 0.9226 |
| 07-Dec-05 | vs St Louis (103) | 75-63 | Won | 0.0798 | -0.0000 |
| 17-Dec-05 | vs Santa Clara (173) | 76-58 | Won | -0.4044 | -0.0000 |
| 21-Dec-05 | at Southern Cal (88) | 59-74 | Lost | 0.9025 | -1.0000 |
| 28-Dec-05 | vs UNC-Asheville (248) | 89-47 | Won | -0.8660 | -0.0000 |
| 03-Jan-06 | vs Davidson (117) | 82-58 | Won | -0.0352 | -0.0000 |
| 07-Jan-06 | vs North Carolina St (22) | 82-69 | Won | 0.8736 | 0.4052 |
| 10-Jan-06 | at Virginia Tech (115) | 64-61 | Won | 0.6687 | 0.2003 |
| 14-Jan-06 | vs Miami FL (76) | 70-81 | Lost | 0.3257 | -1.0000 |
| 19-Jan-06 | at Virginia (66) | 68-72 | Lost | 1.0534 | -1.0000 |
| 22-Jan-06 | at Florida St (36) | 81-80 | Won | 1.3893 | 0.9208 |
| 25-Jan-06 | vs Boston College (16) | 74-81 | Lost | 1.0453 | -1.0000 |
| 28-Jan-06 | vs Arizona (50) | 86-69 | Won | 0.5359 | 0.0675 |
| 02-Feb-06 | at Maryland (45) | 77-62 | Won | 1.2623 | 0.7939 |
| 04-Feb-06 | vs Clemson (59) | 76-61 | Won | 0.4415 | -0.0000 |
| 07-Feb-06 | vs Duke (1) | 83-87 | Lost | 1.7812 | -0.6872 |
| 12-Feb-06 | at Miami FL (76) | 80-70 | Won | 1.0117 | 0.5433 |
| 15-Feb-06 | vs Georgia Tech (122) | 82-75 | Won | -0.0644 | -0.0000 |
| 19-Feb-06 | at Wake Forest (70) | 83-72 | Won | 1.0349 | 0.5665 |
| 22-Feb-06 | at North Carolina St (22) | 95-71 | Won | 1.5597 | 1.0000 |
| 26-Feb-06 | vs Maryland (45) | 81-57 | Won | 0.5762 | 0.1078 |
| 01-Mar-06 | vs Virginia (66) | 99-54 | Won | 0.3674 | -0.0000 |
| 04-Mar-06 | at Duke (1) | 83-76 | Won | 2.4673 | 1.0000 |
| 10-Mar-06 | vs Virginia (66) | 79-67 | Won | 0.7104 | 0.2420 |
| 11-Mar-06 | vs Boston College (16) | 82-85 | Lost | 1.3883 | -1.0000 |
A red opponent rating indicates modification according to home court advantage (0.3430).