| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 19-Nov-05 | vs Eastern Illinois (301) | 80-35 | Won | -1.3511 | -0.0000 |
| 26-Nov-05 | at Purdue (143) | 74-55 | Won | 0.1743 | 0.4672 |
| 29-Nov-05 | vs Coppin St (279) | 81-56 | Won | -1.0762 | -0.0000 |
| 03-Dec-05 | at Illinois (5) | 62-65 | Lost | 1.6416 | -0.0655 |
| 07-Dec-05 | vs Florida A&M (265) | 79-51 | Won | -1.0155 | -0.0000 |
| 11-Dec-05 | at Miami OH (87) | 75-65 | Won | 0.9123 | 1.0000 |
| 18-Dec-05 | at Creighton (46) | 59-61 | Lost | 1.2595 | -0.4476 |
| 22-Dec-05 | vs Troy (214) | 78-54 | Won | -0.6772 | -0.0000 |
| 29-Dec-05 | vs Southern U. (203) | 73-56 | Won | -0.6061 | -0.0000 |
| 04-Jan-06 | at St Joseph's PA (55) | 62-58 | Won | 1.1916 | 1.0000 |
| 07-Jan-06 | vs St Bonaventure (242) | 99-71 | Won | -0.8384 | -0.0000 |
| 09-Jan-06 | vs Eastern Kentucky (194) | 82-63 | Won | -0.5457 | -0.0000 |
| 14-Jan-06 | at Charlotte (92) | 78-65 | Won | 0.8907 | 1.0000 |
| 19-Jan-06 | vs Cincinnati (41) | 73-71 | Won | 0.6314 | 0.9243 |
| 22-Jan-06 | vs St Louis (103) | 54-59 | Lost | 0.0798 | -1.0000 |
| 25-Jan-06 | at Temple (74) | 79-81 | Lost | 1.0184 | -0.6887 |
| 28-Jan-06 | vs Dayton (159) | 60-55 | Won | -0.3222 | -0.0000 |
| 02-Feb-06 | vs George Washington (7) | 85-89 | Lost | 1.2530 | -0.4541 |
| 05-Feb-06 | at St Louis (103) | 47-61 | Lost | 0.7659 | -0.9412 |
| 08-Feb-06 | at Richmond (176) | 63-51 | Won | 0.2549 | 0.5478 |
| 11-Feb-06 | vs La Salle (100) | 70-79 | Lost | 0.1109 | -1.0000 |
| 15-Feb-06 | vs Fordham (132) | 84-64 | Won | -0.1049 | 0.1880 |
| 18-Feb-06 | vs Duquesne (316) | 91-70 | Won | -1.6253 | -0.0000 |
| 21-Feb-06 | at Dayton (159) | 62-66 | Lost | 0.3639 | -1.0000 |
| 25-Feb-06 | at Rhode Island (142) | 85-76 | Won | 0.5222 | 0.8151 |
| 28-Feb-06 | vs St Joseph's PA (55) | 58-68 | Lost | 0.5055 | -1.0000 |
| 04-Mar-06 | at Massachusetts (125) | 56-65 | Lost | 0.6038 | -1.0000 |
| 08-Mar-06 | vs Massachusetts (125) | 75-66 | Won | -0.0822 | 0.2106 |
| 09-Mar-06 | vs Charlotte (92) | 59-55 | Won | 0.2046 | 0.4975 |
| 10-Mar-06 | vs Fordham (132) | 70-59 | Won | -0.1049 | 0.1880 |
| 11-Mar-06 | vs St Joseph's PA (55) | 62-61 | Won | 0.5055 | 0.7984 |
A red opponent rating indicates modification according to home court advantage (0.3430).