| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 19-Nov-05 | at Xavier OH (67) | 35-80 | Lost | 1.0501 | 0.0000 |
| 22-Nov-05 | at St Louis (103) | 45-69 | Lost | 0.4229 | 0.0000 |
| 29-Nov-05 | at Western Illinois (310) | 68-76 | Lost | -0.8689 | -0.8608 |
| 03-Dec-05 | vs Indiana St (136) | 58-66 | Lost | -0.1364 | -0.1283 |
| 08-Dec-05 | vs Tennessee Tech (148) | 80-83 | Lost | -0.2227 | -0.2146 |
| 12-Dec-05 | vs Tennessee St (199) | 68-84 | Lost | -0.5828 | -0.5747 |
| 19-Dec-05 | at Eastern Kentucky (194) | 50-57 | Lost | 0.1404 | 0.0000 |
| 21-Dec-05 | at Morehead St (323) | 57-56 | Won | -1.0977 | 0.9104 |
| 28-Dec-05 | at Missouri (141) | 56-68 | Lost | 0.5306 | 0.0000 |
| 30-Dec-05 | at UMKC (238) | 72-67 | Won | -0.1251 | 1.0000 |
| 05-Jan-06 | vs SE Missouri St (313) | 60-72 | Lost | -1.5691 | -1.0000 |
| 07-Jan-06 | at Austin Peay (175) | 56-62 | Lost | 0.2615 | 0.0000 |
| 09-Jan-06 | at Murray St (78) | 65-66 | Lost | 1.0046 | 0.0000 |
| 12-Jan-06 | vs Tennessee-Martin (207) | 80-70 | Won | -0.6372 | 1.0000 |
| 14-Jan-06 | vs Eastern Kentucky (194) | 46-71 | Lost | -0.5457 | -0.5376 |
| 16-Jan-06 | vs Murray St (78) | 59-54 | Won | 0.3186 | 1.0000 |
| 19-Jan-06 | at Tennessee Tech (148) | 60-75 | Lost | 0.4634 | 0.0000 |
| 21-Jan-06 | at Tennessee St (199) | 57-73 | Lost | 0.1032 | 0.0000 |
| 28-Jan-06 | vs Morehead St (323) | 80-65 | Won | -1.7838 | 0.2243 |
| 02-Feb-06 | at Jacksonville St (182) | 51-66 | Lost | 0.2192 | 0.0000 |
| 04-Feb-06 | at Samford (109) | 55-58 | Lost | 0.7211 | 0.0000 |
| 09-Feb-06 | vs Austin Peay (175) | 61-70 | Lost | -0.4246 | -0.4165 |
| 11-Feb-06 | at Tennessee-Martin (207) | 61-85 | Lost | 0.0488 | 0.0000 |
| 15-Feb-06 | at SE Missouri St (313) | 60-49 | Won | -0.8830 | 1.0000 |
| 18-Feb-06 | vs Eastern Michigan (278) | 50-65 | Lost | -1.0735 | -1.0000 |
| 23-Feb-06 | vs Jacksonville St (182) | 68-75 | Lost | -0.4669 | -0.4588 |
| 25-Feb-06 | vs Samford (109) | 41-52 | Lost | 0.0351 | 0.0000 |
A red opponent rating indicates modification according to home court advantage (0.3430).