| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 26-Nov-05 | vs Middle Tennessee St (128) | 85-79 | Won | -0.0870 | 0.7064 |
| 03-Dec-05 | at Eastern Illinois (301) | 66-58 | Won | -0.6651 | 0.1283 |
| 06-Dec-05 | vs Indiana (24) | 72-67 | Won | 0.8603 | 1.0000 |
| 10-Dec-05 | vs Ball St (211) | 57-56 | Won | -0.6663 | 0.1271 |
| 17-Dec-05 | at Butler (96) | 59-58 | Won | 0.8678 | 1.0000 |
| 19-Dec-05 | vs Campbell (311) | 86-71 | Won | -1.5565 | -0.0000 |
| 22-Dec-05 | vs Illinois St (185) | 69-59 | Won | -0.4733 | 0.3201 |
| 28-Dec-05 | at Wichita St (34) | 62-66 | Lost | 1.3974 | 0.0000 |
| 30-Dec-05 | at Missouri St (42) | 78-97 | Lost | 1.3152 | 0.0000 |
| 02-Jan-06 | vs IPFW (272) | 46-54 | Lost | -1.0629 | -1.0000 |
| 05-Jan-06 | vs Southern Illinois (32) | 49-55 | Lost | 0.7301 | -0.4765 |
| 07-Jan-06 | at Evansville (168) | 58-63 | Lost | 0.3163 | -0.8903 |
| 11-Jan-06 | at Drake (161) | 59-76 | Lost | 0.3524 | -0.8542 |
| 15-Jan-06 | vs Creighton (46) | 53-69 | Lost | 0.5734 | -0.6332 |
| 18-Jan-06 | vs Drake (161) | 68-77 | Lost | -0.3337 | -1.0000 |
| 21-Jan-06 | at Bradley (47) | 63-85 | Lost | 1.2474 | 0.0000 |
| 25-Jan-06 | at Illinois St (185) | 48-75 | Lost | 0.2127 | -0.9939 |
| 29-Jan-06 | vs Missouri St (42) | 58-80 | Lost | 0.6291 | -0.5775 |
| 01-Feb-06 | at Southern Illinois (32) | 63-54 | Won | 1.4162 | 1.0000 |
| 04-Feb-06 | at Northern Iowa (38) | 56-83 | Lost | 1.3739 | 0.0000 |
| 08-Feb-06 | vs Bradley (47) | 75-63 | Won | 0.5614 | 1.0000 |
| 11-Feb-06 | vs Wichita St (34) | 58-77 | Lost | 0.7114 | -0.4953 |
| 14-Feb-06 | vs Northern Iowa (38) | 61-60 | Won | 0.6879 | 1.0000 |
| 18-Feb-06 | at Western Michigan (174) | 59-57 | Won | 0.2817 | 1.0000 |
| 22-Feb-06 | at Creighton (46) | 62-67 | Lost | 1.2595 | 0.0000 |
| 25-Feb-06 | vs Evansville (168) | 75-77 | Lost | -0.3698 | -1.0000 |
| 02-Mar-06 | at Drake (161) | 72-63 | Won | 0.0094 | 0.8028 |
| 03-Mar-06 | at Wichita St (34) | 63-81 | Lost | 1.0544 | -0.1522 |
A red opponent rating indicates modification according to home court advantage (0.3430).