| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 22-Nov-05 | at Cincinnati (41) | 59-76 | Lost | 1.3175 | 0.0000 |
| 26-Nov-05 | vs Western Michigan (174) | 64-47 | Won | -0.4044 | 0.7259 |
| 29-Nov-05 | vs Grambling St (268) | 62-50 | Won | -1.0370 | 0.0933 |
| 03-Dec-05 | vs UW-Green Bay (158) | 59-51 | Won | -0.3047 | 0.8256 |
| 06-Dec-05 | vs IPFW (272) | 65-36 | Won | -1.0629 | 0.0674 |
| 10-Dec-05 | vs Georgia Southern (126) | 61-64 | Lost | -0.0848 | -0.9545 |
| 17-Dec-05 | at CSU-Northridge (254) | 69-73 | Lost | -0.2294 | -1.0000 |
| 22-Dec-05 | at Indiana St (136) | 59-69 | Lost | 0.5496 | -0.3201 |
| 31-Dec-05 | vs Creighton (46) | 53-50 | Won | 0.5734 | 1.0000 |
| 02-Jan-06 | at Northern Iowa (38) | 47-60 | Lost | 1.3739 | 0.0000 |
| 05-Jan-06 | at Creighton (46) | 52-71 | Lost | 1.2595 | 0.0000 |
| 08-Jan-06 | vs Wichita St (34) | 47-56 | Lost | 0.7114 | -0.1584 |
| 11-Jan-06 | at Missouri St (42) | 54-70 | Lost | 1.3152 | 0.0000 |
| 14-Jan-06 | vs Northern Iowa (38) | 52-67 | Lost | 0.6879 | -0.1819 |
| 16-Jan-06 | vs Evansville (168) | 65-57 | Won | -0.3698 | 0.7605 |
| 22-Jan-06 | at Southern Illinois (32) | 44-56 | Lost | 1.4162 | 0.0000 |
| 25-Jan-06 | vs Indiana St (136) | 75-48 | Won | -0.1364 | 0.9939 |
| 28-Jan-06 | vs Southern Illinois (32) | 52-65 | Lost | 0.7301 | -0.1396 |
| 01-Feb-06 | at Bradley (47) | 44-73 | Lost | 1.2474 | 0.0000 |
| 04-Feb-06 | at Evansville (168) | 47-54 | Lost | 0.3163 | -0.5534 |
| 07-Feb-06 | at Drake (161) | 41-45 | Lost | 0.3524 | -0.5173 |
| 11-Feb-06 | vs Bradley (47) | 59-71 | Lost | 0.5614 | -0.3084 |
| 14-Feb-06 | vs Drake (161) | 58-56 | Won | -0.3337 | 0.7966 |
| 18-Feb-06 | at Miami OH (87) | 49-51 | Lost | 0.9123 | 0.0000 |
| 22-Feb-06 | vs Missouri St (42) | 61-72 | Lost | 0.6291 | -0.2406 |
| 25-Feb-06 | at Wichita St (34) | 57-64 | Lost | 1.3974 | 0.0000 |
| 02-Mar-06 | at Evansville (168) | 45-52 | Lost | -0.0267 | -0.8964 |
A red opponent rating indicates modification according to home court advantage (0.3430).