| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 18-Nov-05 | vs Tennessee Tech (148) | 81-60 | Won | -0.2227 | 0.7564 |
| 21-Nov-05 | at Miami OH (87) | 42-58 | Lost | 0.9123 | -0.1086 |
| 23-Nov-05 | vs Morehead St (323) | 67-41 | Won | -1.7838 | -0.0000 |
| 26-Nov-05 | at Creighton (46) | 90-91 | Lost | 1.2595 | 0.0000 |
| 29-Nov-05 | at Cincinnati (41) | 75-66 | Won | 1.3175 | 1.0000 |
| 01-Dec-05 | vs Pepperdine (222) | 63-45 | Won | -0.7018 | 0.2773 |
| 03-Dec-05 | vs Grambling St (268) | 59-55 | Won | -1.0370 | -0.0000 |
| 07-Dec-05 | vs Central Michigan (306) | 61-36 | Won | -1.4753 | -0.0000 |
| 10-Dec-05 | vs DePaul (80) | 54-61 | Lost | 0.2802 | -0.7406 |
| 19-Dec-05 | vs Florida A&M (265) | 73-48 | Won | -1.0155 | -0.0000 |
| 22-Dec-05 | at Cincinnati (41) | 63-81 | Lost | 0.9744 | -0.0465 |
| 23-Dec-05 | vs Northern Iowa (38) | 67-74 | Lost | 1.0309 | 0.0000 |
| 30-Dec-05 | vs Vanderbilt (60) | 60-63 | Lost | 0.3972 | -0.6236 |
| 04-Jan-06 | at Fordham (132) | 56-66 | Lost | 0.5811 | -0.4397 |
| 07-Jan-06 | vs Charlotte (92) | 65-73 | Lost | 0.2046 | -0.8163 |
| 14-Jan-06 | at Richmond (176) | 50-58 | Lost | 0.2549 | -0.7660 |
| 18-Jan-06 | vs Temple (74) | 51-53 | Lost | 0.3323 | -0.6885 |
| 21-Jan-06 | vs Duquesne (316) | 85-63 | Won | -1.6253 | -0.0000 |
| 25-Jan-06 | vs St Bonaventure (242) | 78-58 | Won | -0.8384 | 0.1408 |
| 28-Jan-06 | at Xavier OH (67) | 55-60 | Lost | 1.0501 | 0.0000 |
| 01-Feb-06 | vs St Joseph's PA (55) | 77-69 | Won | 0.5055 | 1.0000 |
| 04-Feb-06 | at Charlotte (92) | 49-62 | Lost | 0.8907 | -0.1302 |
| 08-Feb-06 | at George Washington (7) | 67-81 | Lost | 1.9391 | 0.0000 |
| 11-Feb-06 | vs St Louis (103) | 46-44 | Won | 0.0798 | 1.0000 |
| 18-Feb-06 | at La Salle (100) | 71-74 | Lost | 0.7970 | -0.2239 |
| 21-Feb-06 | vs Xavier OH (67) | 66-62 | Won | 0.3641 | 1.0000 |
| 25-Feb-06 | at Massachusetts (125) | 47-66 | Lost | 0.6038 | -0.4171 |
| 01-Mar-06 | at St Louis (103) | 72-70 | Won | 0.7659 | 1.0000 |
| 04-Mar-06 | vs Rhode Island (142) | 56-65 | Lost | -0.1639 | -1.0000 |
| 08-Mar-06 | at St Joseph's PA (55) | 55-67 | Lost | 0.8486 | -0.1723 |
A red opponent rating indicates modification according to home court advantage (0.3430).