| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 18-Nov-05 | at Michigan (30) | 60-87 | Lost | 1.4252 | 0.0000 |
| 21-Nov-05 | vs UW-Green Bay (158) | 67-62 | Won | -0.3047 | 1.0000 |
| 26-Nov-05 | at UMKC (238) | 65-75 | Lost | -0.1251 | 0.0000 |
| 30-Nov-05 | at Cleveland St (244) | 43-56 | Lost | -0.1560 | -0.0237 |
| 04-Dec-05 | vs Miami OH (87) | 62-75 | Lost | 0.2262 | 0.0000 |
| 07-Dec-05 | at Dayton (159) | 36-61 | Lost | 0.3639 | 0.0000 |
| 18-Dec-05 | vs Southern Illinois (32) | 54-64 | Lost | 0.7301 | 0.0000 |
| 21-Dec-05 | at East Tennessee St (281) | 57-69 | Lost | -0.4103 | -0.2780 |
| 04-Jan-06 | at Bowling Green (257) | 44-66 | Lost | -0.2384 | -0.1061 |
| 07-Jan-06 | vs Kent St (53) | 60-66 | Lost | 0.5137 | 0.0000 |
| 11-Jan-06 | at Miami OH (87) | 49-66 | Lost | 0.9123 | 0.0000 |
| 14-Jan-06 | at Ohio U. (99) | 44-76 | Lost | 0.8172 | 0.0000 |
| 18-Jan-06 | vs Akron (81) | 69-76 | Lost | 0.2756 | 0.0000 |
| 21-Jan-06 | at Buffalo (118) | 71-61 | Won | 0.6503 | 1.0000 |
| 24-Jan-06 | at Ball St (211) | 41-68 | Lost | 0.0198 | 0.0000 |
| 26-Jan-06 | vs Northern Illinois (114) | 43-49 | Lost | -0.0137 | 0.0000 |
| 29-Jan-06 | vs Western Michigan (174) | 71-75 | Lost | -0.4044 | -0.2722 |
| 01-Feb-06 | at Eastern Michigan (278) | 75-81 | Lost | -0.3874 | -0.2551 |
| 04-Feb-06 | at Toledo (135) | 62-78 | Lost | 0.5520 | 0.0000 |
| 11-Feb-06 | vs Buffalo (118) | 59-73 | Lost | -0.0358 | 0.0000 |
| 15-Feb-06 | vs Ball St (211) | 60-63 | Lost | -0.6663 | -0.5340 |
| 18-Feb-06 | vs Morehead St (323) | 87-76 | Won | -1.7838 | 0.3485 |
| 22-Feb-06 | at Northern Illinois (114) | 70-80 | Lost | 0.6724 | 0.0000 |
| 25-Feb-06 | at Western Michigan (174) | 57-68 | Lost | 0.2817 | 0.0000 |
| 01-Mar-06 | vs Eastern Michigan (278) | 69-80 | Lost | -1.0735 | -0.9412 |
| 04-Mar-06 | vs Toledo (135) | 64-66 | Lost | -0.1341 | -0.0018 |
| 06-Mar-06 | at Ohio U. (99) | 53-82 | Lost | 0.8172 | 0.0000 |
A red opponent rating indicates modification according to home court advantage (0.3430).