| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 10-Nov-05 | at Western Carolina (235) | 50-56 | Lost | -0.4507 | -0.8692 |
| 12-Nov-05 | at Virginia Tech (115) | 72-71 | Won | 0.6687 | 1.0000 |
| 13-Nov-05 | at Radford (204) | 63-81 | Lost | -0.2754 | -0.6940 |
| 30-Nov-05 | vs Oakland (260) | 66-76 | Lost | -0.9771 | -1.0000 |
| 03-Dec-05 | at Bradley (47) | 64-93 | Lost | 1.2474 | 0.0000 |
| 10-Dec-05 | at Arkansas-Little Rock (200) | 60-68 | Lost | 0.1029 | -0.3156 |
| 17-Dec-05 | at Florida St (36) | 60-71 | Lost | 1.0462 | 0.0000 |
| 19-Dec-05 | at Troy (214) | 60-52 | Won | 0.0088 | 1.0000 |
| 04-Jan-06 | vs Central Michigan (306) | 66-44 | Won | -1.4753 | 0.1061 |
| 07-Jan-06 | at Western Michigan (174) | 62-84 | Lost | 0.2817 | -0.1369 |
| 11-Jan-06 | vs Northern Illinois (114) | 74-75 | Lost | -0.0137 | -0.4323 |
| 15-Jan-06 | vs Toledo (135) | 59-52 | Won | -0.1341 | 1.0000 |
| 18-Jan-06 | at Eastern Michigan (278) | 79-72 | Won | -0.3874 | 1.0000 |
| 21-Jan-06 | at Ball St (211) | 61-62 | Lost | 0.0198 | -0.3988 |
| 24-Jan-06 | vs Buffalo (118) | 73-76 | Lost | -0.0358 | -0.4544 |
| 26-Jan-06 | at Kent St (53) | 79-74 | Won | 1.1998 | 1.0000 |
| 29-Jan-06 | vs Akron (81) | 72-77 | Lost | 0.2756 | -0.1430 |
| 01-Feb-06 | at Miami OH (87) | 60-77 | Lost | 0.9123 | 0.0000 |
| 04-Feb-06 | vs Ohio U. (99) | 90-93 | Lost | 0.1311 | -0.2874 |
| 07-Feb-06 | vs Eastern Michigan (278) | 73-71 | Won | -1.0735 | 0.5079 |
| 11-Feb-06 | at Toledo (135) | 64-72 | Lost | 0.5520 | 0.0000 |
| 14-Feb-06 | at Akron (81) | 62-77 | Lost | 0.9617 | 0.0000 |
| 18-Feb-06 | vs Wright St (157) | 51-70 | Lost | -0.3042 | -0.7228 |
| 21-Feb-06 | vs Kent St (53) | 66-82 | Lost | 0.5137 | 0.0000 |
| 26-Feb-06 | at Buffalo (118) | 67-81 | Lost | 0.6503 | 0.0000 |
| 01-Mar-06 | vs Miami OH (87) | 59-73 | Lost | 0.2262 | -0.1924 |
| 04-Mar-06 | at Ohio U. (99) | 48-85 | Lost | 0.8172 | 0.0000 |
| 06-Mar-06 | at Toledo (135) | 52-77 | Lost | 0.5520 | 0.0000 |
A red opponent rating indicates modification according to home court advantage (0.3430).