| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 23-Nov-05 | vs Portland St (216) | 72-64 | Won | -0.6847 | -0.0000 |
| 25-Nov-05 | vs Howard (317) | 96-62 | Won | -1.6308 | -0.0000 |
| 26-Nov-05 | vs Iona (48) | 72-89 | Lost | 0.5473 | -0.9885 |
| 29-Nov-05 | vs Northern Iowa (38) | 68-61 | Won | 0.6879 | 1.0000 |
| 03-Dec-05 | vs Fresno St (127) | 77-84 | Lost | -0.0849 | -1.0000 |
| 05-Dec-05 | at Drake (161) | 89-74 | Won | 0.3524 | 0.8166 |
| 09-Dec-05 | vs Iowa (10) | 72-60 | Won | 1.1579 | 1.0000 |
| 17-Dec-05 | vs Ohio State (6) | 67-70 | Lost | 1.6404 | 0.0000 |
| 21-Dec-05 | at South Florida (229) | 83-74 | Won | -0.4167 | 0.0474 |
| 22-Dec-05 | at Northwestern St (72) | 81-77 | Won | 0.6784 | 1.0000 |
| 23-Dec-05 | vs Colorado St (151) | 87-80 | Won | 0.0804 | 0.5446 |
| 28-Dec-05 | vs Tennessee St (199) | 59-51 | Won | -0.5828 | -0.0000 |
| 07-Jan-06 | vs Kansas St (116) | 72-70 | Won | -0.0342 | 0.4299 |
| 09-Jan-06 | vs Texas (8) | 58-78 | Lost | 1.2027 | -0.3332 |
| 14-Jan-06 | at Texas Tech (105) | 73-76 | Lost | 0.7562 | -0.7797 |
| 17-Jan-06 | at Nebraska (65) | 88-75 | Won | 1.0535 | 1.0000 |
| 21-Jan-06 | vs Texas A&M (39) | 81-86 | Lost | 0.6726 | -0.8633 |
| 25-Jan-06 | at Missouri (141) | 82-58 | Won | 0.5306 | 0.9948 |
| 28-Jan-06 | vs Kansas (17) | 85-95 | Lost | 1.0443 | -0.4915 |
| 05-Feb-06 | vs Colorado (51) | 96-79 | Won | 0.5158 | 0.9799 |
| 08-Feb-06 | at Kansas St (116) | 63-66 | Lost | 0.6518 | -0.8840 |
| 11-Feb-06 | at Kansas (17) | 75-88 | Lost | 1.7304 | 0.0000 |
| 15-Feb-06 | vs Nebraska (65) | 63-73 | Lost | 0.3675 | -1.0000 |
| 18-Feb-06 | at Oklahoma (33) | 82-83 | Lost | 1.4075 | -0.1283 |
| 22-Feb-06 | vs Oklahoma St (89) | 68-52 | Won | 0.2145 | 0.6786 |
| 25-Feb-06 | at Baylor (137) | 73-91 | Lost | 0.5464 | -0.9894 |
| 28-Feb-06 | vs Missouri (141) | 85-78 | Won | -0.1554 | 0.3087 |
| 04-Mar-06 | at Colorado (51) | 82-84 | Lost | 1.2018 | -0.3340 |
| 09-Mar-06 | at Oklahoma St (89) | 70-79 | Lost | 0.5575 | -0.9783 |
A red opponent rating indicates modification according to home court advantage (0.3430).