| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 15-Nov-05 | vs Southern U. (203) | 89-56 | Won | -0.6061 | -0.0000 |
| 16-Nov-05 | vs Samford (109) | 77-33 | Won | 0.0351 | -0.0000 |
| 21-Nov-05 | vs West Virginia (26) | 76-75 | Won | 1.1772 | 0.6315 |
| 22-Nov-05 | vs Iowa (10) | 68-59 | Won | 1.5009 | 0.9552 |
| 26-Nov-05 | vs Louisiana-Monroe (256) | 90-55 | Won | -0.9211 | -0.0000 |
| 29-Nov-05 | vs Texas-Pan American (328) | 82-54 | Won | -1.9478 | -0.0000 |
| 03-Dec-05 | vs Texas-Arlington (201) | 93-55 | Won | -0.5949 | -0.0000 |
| 05-Dec-05 | at Rice (215) | 85-58 | Won | -0.3416 | -0.0000 |
| 10-Dec-05 | vs Duke (1) | 66-97 | Lost | 2.1242 | -0.4215 |
| 17-Dec-05 | vs Tennessee (15) | 78-95 | Lost | 1.0684 | -1.0000 |
| 22-Dec-05 | vs Texas St-San Marcos (326) | 85-49 | Won | -1.8733 | -0.0000 |
| 30-Dec-05 | vs Prairie View A&M (332) | 110-38 | Won | -2.3993 | -0.0000 |
| 02-Jan-06 | at Memphis (4) | 69-58 | Won | 2.0433 | 1.0000 |
| 07-Jan-06 | vs Colorado (51) | 89-64 | Won | 0.5158 | -0.0000 |
| 09-Jan-06 | at Iowa St (94) | 78-58 | Won | 0.8789 | 0.3332 |
| 14-Jan-06 | vs Villanova (3) | 58-55 | Won | 1.5456 | 0.9999 |
| 17-Jan-06 | vs Texas Tech (105) | 80-46 | Won | 0.0701 | -0.0000 |
| 21-Jan-06 | at Baylor (137) | 66-47 | Won | 0.5464 | 0.0007 |
| 23-Jan-06 | vs Oklahoma St (89) | 80-46 | Won | 0.2145 | -0.0000 |
| 28-Jan-06 | at Oklahoma (33) | 72-82 | Lost | 1.4075 | -1.0000 |
| 01-Feb-06 | at Missouri (141) | 66-53 | Won | 0.5306 | -0.0000 |
| 04-Feb-06 | vs Texas A&M (39) | 83-70 | Won | 0.6726 | 0.1269 |
| 06-Feb-06 | at Texas Tech (105) | 65-44 | Won | 0.7562 | 0.2105 |
| 11-Feb-06 | vs Nebraska (65) | 78-59 | Won | 0.3675 | -0.0000 |
| 14-Feb-06 | vs Baylor (137) | 90-63 | Won | -0.1397 | -0.0000 |
| 19-Feb-06 | at Oklahoma St (89) | 60-81 | Lost | 0.9005 | -1.0000 |
| 22-Feb-06 | at Kansas St (116) | 65-64 | Won | 0.6518 | 0.1061 |
| 25-Feb-06 | vs Kansas (17) | 80-55 | Won | 1.0443 | 0.4986 |
| 01-Mar-06 | at Texas A&M (39) | 43-46 | Lost | 1.3586 | -1.0000 |
| 05-Mar-06 | vs Oklahoma (33) | 72-48 | Won | 0.7214 | 0.1757 |
| 10-Mar-06 | vs Texas Tech (105) | 77-70 | Won | 0.4132 | -0.0000 |
| 11-Mar-06 | vs Texas A&M (39) | 74-70 | Won | 1.0156 | 0.4699 |
| 12-Mar-06 | vs Kansas (17) | 68-80 | Lost | 1.3874 | -1.0000 |
A red opponent rating indicates modification according to home court advantage (0.3430).