| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 18-Nov-05 | at East Carolina (302) | 75-86 | Lost | -0.6653 | -0.2728 |
| 22-Nov-05 | at Miami FL (76) | 62-87 | Lost | 1.0117 | 0.0000 |
| 30-Nov-05 | vs Radford (204) | 76-83 | Lost | -0.6185 | -0.2261 |
| 03-Dec-05 | vs South Carolina St (233) | 61-62 | Lost | -0.7696 | -0.3771 |
| 07-Dec-05 | at Virginia Tech (115) | 66-94 | Lost | 0.6687 | 0.0000 |
| 14-Dec-05 | at Campbell (311) | 72-93 | Lost | -0.8704 | -0.4780 |
| 19-Dec-05 | at Nebraska (65) | 57-107 | Lost | 1.0535 | 0.0000 |
| 23-Dec-05 | at Southern Cal (88) | 38-68 | Lost | 0.9025 | 0.0000 |
| 27-Dec-05 | at Hawai`i (101) | 60-66 | Lost | 0.7944 | 0.0000 |
| 30-Dec-05 | at Cincinnati (41) | 69-105 | Lost | 1.3175 | 0.0000 |
| 04-Jan-06 | at MD-Eastern Shore (318) | 75-77 | Lost | -0.9650 | -0.5726 |
| 09-Jan-06 | at Delaware St (167) | 52-56 | Lost | 0.3170 | 0.0000 |
| 14-Jan-06 | vs Florida A&M (265) | 71-75 | Lost | -1.0155 | -0.6231 |
| 16-Jan-06 | vs Bethune-Cookman (275) | 69-67 | Won | -1.0677 | 1.0000 |
| 21-Jan-06 | vs Coppin St (279) | 78-71 | Won | -1.0762 | 1.0000 |
| 23-Jan-06 | vs Morgan St (329) | 60-42 | Won | -2.0568 | 0.3356 |
| 28-Jan-06 | at Norfolk St (269) | 43-55 | Lost | -0.3606 | 0.0000 |
| 30-Jan-06 | at Hampton (274) | 65-77 | Lost | -0.3804 | 0.0000 |
| 02-Feb-06 | at Longwood (303) | 77-83 | Lost | -0.7072 | -0.3147 |
| 06-Feb-06 | vs Delaware St (167) | 45-48 | Lost | -0.3690 | 0.0000 |
| 11-Feb-06 | at Bethune-Cookman (275) | 55-69 | Lost | -0.3817 | 0.0000 |
| 13-Feb-06 | at Florida A&M (265) | 73-70 | Won | -0.3294 | 1.0000 |
| 18-Feb-06 | at Coppin St (279) | 64-65 | Lost | -0.3901 | 0.0000 |
| 20-Feb-06 | at Morgan St (329) | 56-52 | Won | -1.3707 | 1.0000 |
| 25-Feb-06 | vs Norfolk St (269) | 60-75 | Lost | -1.0467 | -0.6543 |
| 27-Feb-06 | vs Hampton (274) | 65-60 | Won | -1.0665 | 1.0000 |
| 01-Mar-06 | vs Howard (317) | 50-58 | Lost | -1.6308 | -1.0000 |
| 03-Mar-06 | at South Carolina St (233) | 44-51 | Lost | -0.0835 | 0.0000 |
| 07-Mar-06 | vs Howard (317) | 52-62 | Lost | -1.2877 | -0.8953 |
A red opponent rating indicates modification according to home court advantage (0.3430).