| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 20-Nov-05 | vs Chicago St (228) | 81-52 | Won | -0.7664 | -0.0000 |
| 22-Nov-05 | vs Butler (88) | 79-69 | Won | 0.2144 | -0.0000 |
| 28-Nov-05 | vs Virginia Tech (117) | 69-56 | Won | -0.0367 | -0.0000 |
| 10-Dec-05 | at St Joseph's PA (58) | 81-74 | Won | 1.1705 | 0.6675 |
| 12-Dec-05 | vs Norfolk St (267) | 92-59 | Won | -1.0457 | -0.0000 |
| 14-Dec-05 | vs Belmont (199) | 85-75 | Won | -0.5839 | -0.0000 |
| 17-Dec-05 | at Iowa St (99) | 70-67 | Won | 0.4857 | -0.0000 |
| 23-Dec-05 | vs Tennessee St (202) | 74-65 | Won | -0.5983 | -0.0000 |
| 28-Dec-05 | vs Gardner-Webb (214) | 87-58 | Won | -0.6968 | -0.0000 |
| 31-Dec-05 | vs LSU (6) | 78-76 | Won | 1.2778 | 0.7747 |
| 05-Jan-06 | vs Penn St (94) | 104-69 | Won | 0.1710 | -0.0000 |
| 07-Jan-06 | at Indiana (29) | 79-81 | Lost | 1.4808 | -1.0000 |
| 11-Jan-06 | at Purdue (148) | 80-64 | Won | 0.4687 | -0.0000 |
| 15-Jan-06 | vs Michigan St (30) | 59-62 | Lost | 0.7657 | -1.0000 |
| 18-Jan-06 | vs Wisconsin (37) | 77-67 | Won | 0.6846 | 0.1815 |
| 21-Jan-06 | at Penn St (94) | 75-64 | Won | 0.8648 | 0.3617 |
| 28-Jan-06 | at Iowa (17) | 62-67 | Lost | 1.7251 | -0.7779 |
| 30-Jan-06 | vs Florida A&M (262) | 95-53 | Won | -1.0152 | -0.0000 |
| 04-Feb-06 | vs Minnesota (70) | 67-53 | Won | 0.3297 | -0.0000 |
| 09-Feb-06 | at Michigan (33) | 94-85 | Won | 1.4079 | 0.9048 |
| 12-Feb-06 | vs Illinois (9) | 69-53 | Won | 1.1917 | 0.6886 |
| 15-Feb-06 | at Wisconsin (37) | 73-78 | Lost | 1.3783 | -1.0000 |
| 18-Feb-06 | vs Northwestern (86) | 61-52 | Won | 0.2218 | -0.0000 |
| 22-Feb-06 | at Michigan St (30) | 79-68 | Won | 1.4595 | 0.9564 |
| 25-Feb-06 | vs Michigan (33) | 64-54 | Won | 0.7141 | 0.2111 |
| 01-Mar-06 | at Northwestern (86) | 56-53 | Won | 0.9155 | 0.4125 |
| 05-Mar-06 | vs Purdue (148) | 76-57 | Won | -0.2250 | -0.0000 |
| 10-Mar-06 | vs Penn St (94) | 63-56 | Won | 0.5179 | 0.0148 |
| 11-Mar-06 | at Indiana (29) | 52-51 | Won | 1.1339 | 0.6309 |
| 12-Mar-06 | vs Iowa (17) | 60-67 | Lost | 1.3783 | -1.0000 |
| 17-Mar-06 | vs Davidson (118) | 70-62 | Won | 0.3005 | -0.0000 |
| 19-Mar-06 | vs Georgetown DC (15) | 52-70 | Lost | 1.3920 | -1.0000 |
A red opponent rating indicates modification according to home court advantage (0.3469).