| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 18-Nov-05 | vs Norfolk St (267) | 80-51 | Won | -0.6988 | -0.0000 |
| 19-Nov-05 | vs Eastern Kentucky (193) | 95-89 | Won | -0.2070 | -0.0000 |
| 21-Nov-05 | vs Old Dominion (56) | 84-81 | Won | 0.8328 | 0.8013 |
| 26-Nov-05 | vs Coastal Carolina (143) | 92-54 | Won | -0.1888 | -0.0000 |
| 29-Nov-05 | at Wake Forest (77) | 88-91 | Lost | 0.9892 | -1.0000 |
| 03-Dec-05 | vs Pepperdine (223) | 71-55 | Won | -0.7139 | -0.0000 |
| 07-Dec-05 | vs UW-Green Bay (158) | 82-62 | Won | -0.3008 | -0.0000 |
| 10-Dec-05 | vs Marquette (36) | 77-63 | Won | 0.6985 | 0.6671 |
| 12-Dec-05 | vs UNC-Wilmington (34) | 54-51 | Won | 0.7108 | 0.6793 |
| 15-Dec-05 | vs UW-Milwaukee (57) | 74-68 | Won | 0.4782 | 0.4468 |
| 28-Dec-05 | vs Louisiana Tech (96) | 78-52 | Won | 0.1528 | 0.1213 |
| 31-Dec-05 | at Pittsburgh (13) | 64-73 | Lost | 1.8114 | -0.2201 |
| 05-Jan-06 | vs Iowa (17) | 66-52 | Won | 1.0314 | 0.9999 |
| 08-Jan-06 | vs Michigan St (30) | 82-63 | Won | 0.7657 | 0.7343 |
| 10-Jan-06 | at Minnesota (70) | 64-62 | Won | 1.0235 | 0.9920 |
| 14-Jan-06 | vs Northwestern (86) | 68-52 | Won | 0.2218 | 0.1903 |
| 18-Jan-06 | at Ohio State (11) | 67-77 | Lost | 1.8499 | -0.1815 |
| 21-Jan-06 | vs North Dakota St (218) | 55-62 | Lost | -0.7031 | -1.0000 |
| 25-Jan-06 | vs Penn St (94) | 72-43 | Won | 0.1710 | 0.1396 |
| 28-Jan-06 | at Michigan (33) | 76-85 | Lost | 1.4079 | -0.6235 |
| 31-Jan-06 | vs Illinois (9) | 51-66 | Lost | 1.1917 | -0.8398 |
| 04-Feb-06 | at Purdue (148) | 62-70 | Lost | 0.4687 | -1.0000 |
| 08-Feb-06 | vs Indiana (29) | 72-54 | Won | 0.7870 | 0.7556 |
| 11-Feb-06 | at Penn St (94) | 82-62 | Won | 0.8648 | 0.8333 |
| 15-Feb-06 | vs Ohio State (11) | 78-73 | Won | 1.1562 | 1.0000 |
| 23-Feb-06 | at Northwestern (86) | 51-62 | Lost | 0.9155 | -1.0000 |
| 26-Feb-06 | vs Minnesota (70) | 80-74 | Won | 0.3297 | 0.2983 |
| 02-Mar-06 | at Michigan St (30) | 65-74 | Lost | 1.4595 | -0.5720 |
| 04-Mar-06 | at Iowa (17) | 44-59 | Lost | 1.7251 | -0.3063 |
| 10-Mar-06 | vs Indiana (29) | 56-61 | Lost | 1.1339 | -0.8975 |
| 17-Mar-06 | at Arizona (42) | 75-94 | Lost | 0.9905 | -1.0000 |
A red opponent rating indicates modification according to home court advantage (0.3469).