| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 18-Nov-05 | vs North Dakota St (218) | 70-57 | Won | -0.7031 | -0.0000 |
| 26-Nov-05 | vs Chattanooga (187) | 67-46 | Won | -0.4879 | -0.0000 |
| 28-Nov-05 | vs Gardner-Webb (214) | 72-73 | Lost | -0.6968 | -1.0000 |
| 30-Nov-05 | at Maryland (55) | 66-83 | Lost | 1.1820 | -0.4946 |
| 03-Dec-05 | vs Coastal Carolina (143) | 75-57 | Won | -0.1888 | 0.1346 |
| 05-Dec-05 | at Arizona St (159) | 85-79 | Won | 0.3912 | 0.7146 |
| 10-Dec-05 | vs UNLV (108) | 72-67 | Won | 0.0456 | 0.3690 |
| 14-Dec-05 | vs Alabama-Birmingham (50) | 69-68 | Won | 0.5467 | 0.8701 |
| 21-Dec-05 | vs Grambling St (272) | 88-64 | Won | -1.0724 | -0.0000 |
| 23-Dec-05 | vs South Dakota St (265) | 80-61 | Won | -1.0352 | -0.0000 |
| 31-Dec-05 | vs Oral Roberts (142) | 67-54 | Won | -0.1856 | 0.1378 |
| 07-Jan-06 | vs Northwestern (86) | 49-57 | Lost | 0.2218 | -1.0000 |
| 10-Jan-06 | vs Wisconsin (37) | 62-64 | Lost | 0.6846 | -0.9920 |
| 14-Jan-06 | at Purdue (148) | 55-72 | Lost | 0.4687 | -1.0000 |
| 18-Jan-06 | at Iowa (17) | 72-76 | Lost | 1.7251 | 0.0000 |
| 21-Jan-06 | vs Michigan (33) | 55-71 | Lost | 0.7141 | -0.9625 |
| 25-Jan-06 | at Illinois (9) | 53-77 | Lost | 1.8854 | 0.0000 |
| 29-Jan-06 | vs Indiana (29) | 61-42 | Won | 0.7870 | 1.0000 |
| 04-Feb-06 | at Ohio State (11) | 53-67 | Lost | 1.8499 | 0.0000 |
| 08-Feb-06 | at Penn St (94) | 77-66 | Won | 0.8648 | 1.0000 |
| 11-Feb-06 | vs Michigan St (30) | 69-55 | Won | 0.7657 | 1.0000 |
| 15-Feb-06 | at Michigan (33) | 50-72 | Lost | 1.4079 | -0.2687 |
| 18-Feb-06 | vs Iowa (17) | 74-61 | Won | 1.0314 | 1.0000 |
| 22-Feb-06 | vs Purdue (148) | 62-50 | Won | -0.2250 | 0.0984 |
| 26-Feb-06 | at Wisconsin (37) | 74-80 | Lost | 1.3783 | -0.2983 |
| 28-Feb-06 | vs Illinois (9) | 65-71 | Lost | 1.1917 | -0.4850 |
| 04-Mar-06 | at Northwestern (86) | 53-57 | Lost | 0.9155 | -0.7611 |
| 09-Mar-06 | at Michigan (33) | 59-55 | Won | 1.0610 | 1.0000 |
| 10-Mar-06 | at Iowa (17) | 57-67 | Lost | 1.3783 | -0.2983 |
| 15-Mar-06 | vs Wake Forest (77) | 73-58 | Won | 0.2954 | 0.6188 |
| 21-Mar-06 | at Cincinnati (45) | 62-76 | Lost | 1.3058 | -0.3708 |
A red opponent rating indicates modification according to home court advantage (0.3469).