| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 19-Nov-05 | vs Murray St (76) | 79-75 | Won | 0.2969 | 0.3379 |
| 22-Nov-05 | vs Illinois St (185) | 76-59 | Won | -0.4754 | -0.0000 |
| 25-Nov-05 | vs Holy Cross (126) | 77-55 | Won | -0.0922 | -0.0000 |
| 29-Nov-05 | vs Dayton (161) | 66-75 | Lost | -0.3316 | -1.0000 |
| 03-Dec-05 | vs Memphis (5) | 81-91 | Lost | 1.3856 | -0.5734 |
| 10-Dec-05 | at Vanderbilt (61) | 92-83 | Won | 1.1362 | 1.0000 |
| 14-Dec-05 | vs Ohio U. (101) | 86-58 | Won | 0.1359 | 0.1770 |
| 17-Dec-05 | vs Tennessee Tech (150) | 105-62 | Won | -0.2294 | -0.0000 |
| 22-Dec-05 | vs Dayton (161) | 81-63 | Won | 0.0153 | 0.0563 |
| 23-Dec-05 | vs LSU (6) | 75-72 | Won | 1.6246 | 1.0000 |
| 28-Dec-05 | vs Miami OH (90) | 75-65 | Won | 0.1949 | 0.2360 |
| 30-Dec-05 | vs North Carolina A&T (320) | 105-69 | Won | -1.7481 | -0.0000 |
| 04-Jan-06 | vs DePaul (79) | 82-60 | Won | 0.2883 | 0.3293 |
| 07-Jan-06 | at Marquette (36) | 70-66 | Won | 1.3923 | 1.0000 |
| 09-Jan-06 | at Connecticut (2) | 59-70 | Lost | 2.3673 | 0.0000 |
| 14-Jan-06 | vs Syracuse (23) | 58-77 | Lost | 0.8865 | -1.0000 |
| 19-Jan-06 | at Xavier OH (71) | 71-73 | Lost | 1.0213 | -0.9377 |
| 22-Jan-06 | vs Rutgers (54) | 71-66 | Won | 0.4933 | 0.5343 |
| 25-Jan-06 | at Louisville (52) | 50-67 | Lost | 1.2331 | -0.7258 |
| 28-Jan-06 | at Georgetown DC (15) | 57-76 | Lost | 1.7389 | -0.2200 |
| 31-Jan-06 | vs South Florida (230) | 73-60 | Won | -0.7756 | -0.0000 |
| 04-Feb-06 | at West Virginia (24) | 57-66 | Lost | 1.5662 | -0.3928 |
| 06-Feb-06 | vs Louisville (52) | 74-68 | Won | 0.5394 | 0.5804 |
| 12-Feb-06 | at Pittsburgh (13) | 69-89 | Lost | 1.8114 | -0.1476 |
| 15-Feb-06 | at Syracuse (23) | 82-65 | Won | 1.5803 | 1.0000 |
| 17-Feb-06 | vs Providence RI (93) | 66-64 | Won | 0.1796 | 0.2206 |
| 23-Feb-06 | vs Villanova (3) | 72-74 | Lost | 1.5125 | -0.4465 |
| 28-Feb-06 | at Seton Hall (59) | 62-72 | Lost | 1.1565 | -0.8025 |
| 04-Mar-06 | vs West Virginia (24) | 78-75 | Won | 0.8724 | 0.9134 |
| 08-Mar-06 | vs Syracuse (23) | 73-74 | Lost | 1.2334 | -0.7256 |
| 17-Mar-06 | vs Charlotte (91) | 86-80 | Won | 0.1917 | 0.2328 |
| 21-Mar-06 | vs Minnesota (70) | 76-62 | Won | 0.3297 | 0.3708 |
| 23-Mar-06 | vs South Carolina (43) | 62-65 | Lost | 0.6329 | -1.0000 |
A red opponent rating indicates modification according to home court advantage (0.3469).