| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 18-Nov-05 | vs Tennessee Tech (150) | 81-60 | Won | -0.2294 | 0.7554 |
| 21-Nov-05 | at Miami OH (90) | 42-58 | Lost | 0.8887 | -0.1266 |
| 23-Nov-05 | vs Morehead St (323) | 67-41 | Won | -1.8077 | -0.0000 |
| 26-Nov-05 | at Creighton (49) | 90-91 | Lost | 1.2472 | 0.0000 |
| 29-Nov-05 | at Cincinnati (45) | 75-66 | Won | 1.3058 | 1.0000 |
| 01-Dec-05 | vs Pepperdine (223) | 63-45 | Won | -0.7139 | 0.2708 |
| 03-Dec-05 | vs Grambling St (272) | 59-55 | Won | -1.0724 | -0.0000 |
| 07-Dec-05 | vs Central Michigan (306) | 61-36 | Won | -1.4854 | -0.0000 |
| 10-Dec-05 | vs DePaul (79) | 54-61 | Lost | 0.2883 | -0.7270 |
| 19-Dec-05 | vs Florida A&M (262) | 73-48 | Won | -1.0152 | -0.0000 |
| 22-Dec-05 | at Cincinnati (45) | 63-81 | Lost | 0.9590 | -0.0563 |
| 23-Dec-05 | vs Northern Iowa (41) | 67-74 | Lost | 1.0001 | -0.0152 |
| 30-Dec-05 | vs Vanderbilt (61) | 60-63 | Lost | 0.4424 | -0.5729 |
| 04-Jan-06 | at Fordham (127) | 56-66 | Lost | 0.5967 | -0.4186 |
| 07-Jan-06 | vs Charlotte (91) | 65-73 | Lost | 0.1917 | -0.8236 |
| 14-Jan-06 | at Richmond (176) | 50-58 | Lost | 0.2542 | -0.7611 |
| 18-Jan-06 | vs Temple (78) | 51-53 | Lost | 0.2947 | -0.7206 |
| 21-Jan-06 | vs Duquesne (317) | 85-63 | Won | -1.6447 | -0.0000 |
| 25-Jan-06 | vs St Bonaventure (244) | 78-58 | Won | -0.8490 | 0.1357 |
| 28-Jan-06 | at Xavier OH (71) | 55-60 | Lost | 1.0213 | 0.0000 |
| 01-Feb-06 | vs St Joseph's PA (58) | 77-69 | Won | 0.4768 | 1.0000 |
| 04-Feb-06 | at Charlotte (91) | 49-62 | Lost | 0.8855 | -0.1298 |
| 08-Feb-06 | at George Washington (8) | 67-81 | Lost | 1.9179 | 0.0000 |
| 11-Feb-06 | vs St Louis (106) | 46-44 | Won | 0.0676 | 1.0000 |
| 18-Feb-06 | at La Salle (103) | 71-74 | Lost | 0.8093 | -0.2059 |
| 21-Feb-06 | vs Xavier OH (71) | 66-62 | Won | 0.3275 | 1.0000 |
| 25-Feb-06 | at Massachusetts (125) | 47-66 | Lost | 0.6029 | -0.4124 |
| 01-Mar-06 | at St Louis (106) | 72-70 | Won | 0.7613 | 1.0000 |
| 04-Mar-06 | vs Rhode Island (141) | 56-65 | Lost | -0.1730 | -1.0000 |
| 08-Mar-06 | at St Joseph's PA (58) | 55-67 | Lost | 0.8236 | -0.1917 |
A red opponent rating indicates modification according to home court advantage (0.3469).