| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 19-Nov-05 | vs Old Dominion (56) | 52-65 | Lost | 0.8328 | -0.4170 |
| 20-Nov-05 | vs Georgia (85) | 68-79 | Lost | 0.6015 | -0.6483 |
| 21-Nov-05 | vs Norfolk St (267) | 72-53 | Won | -0.6988 | 0.0514 |
| 26-Nov-05 | vs St Francis NY (285) | 60-66 | Lost | -1.1190 | -1.0000 |
| 28-Nov-05 | at Siena (139) | 54-64 | Lost | 0.5551 | -0.6947 |
| 01-Dec-05 | vs Iona (51) | 70-71 | Lost | 0.5463 | -0.7035 |
| 04-Dec-05 | at Holy Cross (126) | 63-71 | Lost | 0.6016 | -0.6482 |
| 07-Dec-05 | at Virginia (75) | 62-60 | Won | 0.9989 | 1.0000 |
| 14-Dec-05 | at Fairfield (204) | 95-80 | Won | 0.0727 | 0.8229 |
| 23-Dec-05 | at Manhattan (81) | 68-81 | Lost | 0.9688 | -0.2810 |
| 28-Dec-05 | at Notre Dame (64) | 49-85 | Lost | 1.0983 | -0.1515 |
| 31-Dec-05 | vs Lafayette (269) | 71-52 | Won | -1.0593 | -0.0000 |
| 04-Jan-06 | vs Dayton (161) | 66-56 | Won | -0.3316 | 0.4186 |
| 07-Jan-06 | at Rhode Island (141) | 59-64 | Lost | 0.5208 | -0.7290 |
| 09-Jan-06 | vs Pennsylvania (121) | 78-63 | Won | -0.0743 | 0.6759 |
| 15-Jan-06 | vs Duquesne (317) | 90-63 | Won | -1.6447 | -0.0000 |
| 18-Jan-06 | at Massachusetts (125) | 61-74 | Lost | 0.6029 | -0.6469 |
| 21-Jan-06 | vs St Bonaventure (244) | 79-72 | Won | -0.8490 | -0.0000 |
| 28-Jan-06 | at St Louis (106) | 54-64 | Lost | 0.7613 | -0.4885 |
| 01-Feb-06 | vs Richmond (176) | 63-45 | Won | -0.4396 | 0.3106 |
| 04-Feb-06 | at Duquesne (317) | 90-81 | Won | -0.9509 | -0.0000 |
| 09-Feb-06 | at St Bonaventure (244) | 81-70 | Won | -0.1552 | 0.5950 |
| 12-Feb-06 | vs Rhode Island (141) | 79-76 | Won | -0.1730 | 0.5772 |
| 15-Feb-06 | at Xavier OH (71) | 64-84 | Lost | 1.0213 | -0.2285 |
| 18-Feb-06 | vs Charlotte (91) | 75-81 | Lost | 0.1917 | -1.0000 |
| 22-Feb-06 | at St Joseph's PA (58) | 58-64 | Lost | 1.1705 | -0.0793 |
| 25-Feb-06 | vs George Washington (8) | 67-78 | Lost | 1.2241 | -0.0257 |
| 01-Mar-06 | vs La Salle (103) | 83-74 | Won | 0.1156 | 0.8658 |
| 05-Mar-06 | at Temple (78) | 69-52 | Won | 0.9885 | 1.0000 |
| 08-Mar-06 | vs Richmond (176) | 45-37 | Won | -0.0927 | 0.6575 |
| 09-Mar-06 | at La Salle (103) | 64-62 | Won | 0.4625 | 1.0000 |
| 10-Mar-06 | at Xavier OH (71) | 59-70 | Lost | 1.0213 | -0.2285 |
A red opponent rating indicates modification according to home court advantage (0.3469).