| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 18-Nov-05 | at Michigan (33) | 60-87 | Lost | 1.4079 | 0.0000 |
| 21-Nov-05 | vs UW-Green Bay (158) | 67-62 | Won | -0.3008 | 1.0000 |
| 26-Nov-05 | at UMKC (240) | 65-75 | Lost | -0.1368 | 0.0000 |
| 30-Nov-05 | at Cleveland St (241) | 43-56 | Lost | -0.1374 | 0.0000 |
| 04-Dec-05 | vs Miami OH (90) | 62-75 | Lost | 0.1949 | 0.0000 |
| 07-Dec-05 | at Dayton (161) | 36-61 | Lost | 0.3622 | 0.0000 |
| 18-Dec-05 | vs Southern Illinois (35) | 54-64 | Lost | 0.6998 | 0.0000 |
| 21-Dec-05 | at East Tennessee St (286) | 57-69 | Lost | -0.4276 | -0.2891 |
| 04-Jan-06 | at Bowling Green (256) | 44-66 | Lost | -0.2330 | -0.0945 |
| 07-Jan-06 | vs Kent St (53) | 60-66 | Lost | 0.4947 | 0.0000 |
| 11-Jan-06 | at Miami OH (90) | 49-66 | Lost | 0.8887 | 0.0000 |
| 14-Jan-06 | at Ohio U. (101) | 44-76 | Lost | 0.8297 | 0.0000 |
| 18-Jan-06 | vs Akron (74) | 69-76 | Lost | 0.3060 | 0.0000 |
| 21-Jan-06 | at Buffalo (116) | 71-61 | Won | 0.6598 | 1.0000 |
| 24-Jan-06 | at Ball St (209) | 41-68 | Lost | 0.0341 | 0.0000 |
| 26-Jan-06 | vs Northern Illinois (115) | 43-49 | Lost | -0.0107 | 0.0000 |
| 29-Jan-06 | vs Western Michigan (170) | 71-75 | Lost | -0.3981 | -0.2596 |
| 01-Feb-06 | at Eastern Michigan (276) | 75-81 | Lost | -0.3850 | -0.2465 |
| 04-Feb-06 | at Toledo (134) | 62-78 | Lost | 0.5748 | 0.0000 |
| 11-Feb-06 | vs Buffalo (116) | 59-73 | Lost | -0.0340 | 0.0000 |
| 15-Feb-06 | vs Ball St (209) | 60-63 | Lost | -0.6597 | -0.5212 |
| 18-Feb-06 | vs Morehead St (323) | 87-76 | Won | -1.8077 | 0.3308 |
| 22-Feb-06 | at Northern Illinois (115) | 70-80 | Lost | 0.6831 | 0.0000 |
| 25-Feb-06 | at Western Michigan (170) | 57-68 | Lost | 0.2957 | 0.0000 |
| 01-Mar-06 | vs Eastern Michigan (276) | 69-80 | Lost | -1.0788 | -0.9403 |
| 04-Mar-06 | vs Toledo (134) | 64-66 | Lost | -0.1190 | 0.0000 |
| 06-Mar-06 | at Ohio U. (101) | 53-82 | Lost | 0.8297 | 0.0000 |
A red opponent rating indicates modification according to home court advantage (0.3469).