| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 10-Nov-05 | at Western Carolina (233) | 50-56 | Lost | -0.4346 | -0.8547 |
| 12-Nov-05 | at Virginia Tech (117) | 72-71 | Won | 0.6570 | 1.0000 |
| 13-Nov-05 | at Radford (203) | 63-81 | Lost | -0.2735 | -0.6935 |
| 30-Nov-05 | vs Oakland (261) | 66-76 | Lost | -0.9975 | -1.0000 |
| 03-Dec-05 | at Bradley (38) | 64-93 | Lost | 1.3743 | 0.0000 |
| 10-Dec-05 | at Arkansas-Little Rock (200) | 60-68 | Lost | 0.0979 | -0.3221 |
| 17-Dec-05 | at Florida St (47) | 60-71 | Lost | 0.9395 | 0.0000 |
| 19-Dec-05 | at Troy (213) | 60-52 | Won | 0.0046 | 1.0000 |
| 04-Jan-06 | vs Central Michigan (306) | 66-44 | Won | -1.4854 | 0.0945 |
| 07-Jan-06 | at Western Michigan (170) | 62-84 | Lost | 0.2957 | -0.1244 |
| 11-Jan-06 | vs Northern Illinois (115) | 74-75 | Lost | -0.0107 | -0.4307 |
| 15-Jan-06 | vs Toledo (134) | 59-52 | Won | -0.1190 | 1.0000 |
| 18-Jan-06 | at Eastern Michigan (276) | 79-72 | Won | -0.3850 | 1.0000 |
| 21-Jan-06 | at Ball St (209) | 61-62 | Lost | 0.0341 | -0.3860 |
| 24-Jan-06 | vs Buffalo (116) | 73-76 | Lost | -0.0340 | -0.4540 |
| 26-Jan-06 | at Kent St (53) | 79-74 | Won | 1.1885 | 1.0000 |
| 29-Jan-06 | vs Akron (74) | 72-77 | Lost | 0.3060 | -0.1140 |
| 01-Feb-06 | at Miami OH (90) | 60-77 | Lost | 0.8887 | 0.0000 |
| 04-Feb-06 | vs Ohio U. (101) | 90-93 | Lost | 0.1359 | -0.2841 |
| 07-Feb-06 | vs Eastern Michigan (276) | 73-71 | Won | -1.0788 | 0.5012 |
| 11-Feb-06 | at Toledo (134) | 64-72 | Lost | 0.5748 | 0.0000 |
| 14-Feb-06 | at Akron (74) | 62-77 | Lost | 0.9998 | 0.0000 |
| 18-Feb-06 | vs Wright St (157) | 51-70 | Lost | -0.2972 | -0.7172 |
| 21-Feb-06 | vs Kent St (53) | 66-82 | Lost | 0.4947 | 0.0000 |
| 26-Feb-06 | at Buffalo (116) | 67-81 | Lost | 0.6598 | 0.0000 |
| 01-Mar-06 | vs Miami OH (90) | 59-73 | Lost | 0.1949 | -0.2251 |
| 04-Mar-06 | at Ohio U. (101) | 48-85 | Lost | 0.8297 | 0.0000 |
| 06-Mar-06 | at Toledo (134) | 52-77 | Lost | 0.5748 | 0.0000 |
A red opponent rating indicates modification according to home court advantage (0.3469).