| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 19-Nov-05 | at DePaul (79) | 75-60 | Won | 0.9821 | 0.9546 |
| 26-Nov-05 | vs Chicago St (228) | 68-58 | Won | -0.7664 | -0.0000 |
| 30-Nov-05 | at Loyola-Chicago (114) | 72-86 | Lost | 0.7110 | -1.0000 |
| 03-Dec-05 | vs Bowling Green (256) | 93-64 | Won | -0.9268 | -0.0000 |
| 06-Dec-05 | at Butler (88) | 60-70 | Lost | 0.9082 | -1.0000 |
| 14-Dec-05 | vs Western Kentucky (82) | 78-76 | Won | 0.2734 | 0.2460 |
| 17-Dec-05 | vs Delaware St (151) | 68-46 | Won | -0.2342 | -0.0000 |
| 21-Dec-05 | at Southern Miss (248) | 56-43 | Won | -0.1877 | -0.0000 |
| 28-Dec-05 | vs Northern Iowa (41) | 68-60 | Won | 0.6532 | 0.6258 |
| 30-Dec-05 | at Wichita St (31) | 67-69 | Lost | 1.4469 | -0.5806 |
| 02-Jan-06 | vs Creighton (49) | 86-69 | Won | 0.5534 | 0.5259 |
| 05-Jan-06 | at Drake (162) | 73-75 | Lost | 0.3520 | -1.0000 |
| 08-Jan-06 | at Southern Illinois (35) | 55-67 | Lost | 1.3936 | -0.6339 |
| 11-Jan-06 | vs Wichita St (31) | 76-86 | Lost | 0.7531 | -1.0000 |
| 14-Jan-06 | vs Evansville (168) | 90-62 | Won | -0.3696 | -0.0000 |
| 18-Jan-06 | at Creighton (49) | 76-80 | Lost | 1.2472 | -0.7803 |
| 21-Jan-06 | vs Indiana St (136) | 85-63 | Won | -0.1373 | -0.0000 |
| 25-Jan-06 | vs Missouri St (44) | 86-76 | Won | 0.6324 | 0.6050 |
| 28-Jan-06 | at Evansville (168) | 79-76 | Won | 0.3242 | 0.2967 |
| 01-Feb-06 | vs Illinois St (185) | 73-44 | Won | -0.4754 | -0.0000 |
| 04-Feb-06 | at Missouri St (44) | 62-70 | Lost | 1.3262 | -0.7013 |
| 08-Feb-06 | at Indiana St (136) | 63-75 | Lost | 0.5565 | -1.0000 |
| 11-Feb-06 | at Illinois St (185) | 71-59 | Won | 0.2183 | 0.1909 |
| 14-Feb-06 | vs Southern Illinois (35) | 72-60 | Won | 0.6998 | 0.6724 |
| 18-Feb-06 | vs Tennessee Tech (150) | 77-62 | Won | -0.2294 | -0.0000 |
| 22-Feb-06 | at Northern Iowa (41) | 71-49 | Won | 1.3470 | 1.0000 |
| 25-Feb-06 | vs Drake (162) | 86-66 | Won | -0.3417 | -0.0000 |
| 03-Mar-06 | at Creighton (49) | 54-47 | Won | 0.9003 | 0.8728 |
| 04-Mar-06 | vs Wichita St (31) | 60-52 | Won | 1.1000 | 1.0000 |
| 05-Mar-06 | at Southern Illinois (35) | 46-59 | Lost | 1.0467 | -0.9807 |
| 17-Mar-06 | at Kansas (21) | 77-73 | Won | 1.2657 | 1.0000 |
| 19-Mar-06 | at Pittsburgh (13) | 72-66 | Won | 1.4645 | 1.0000 |
| 23-Mar-06 | at Memphis (5) | 64-80 | Lost | 1.7325 | -0.2950 |
A red opponent rating indicates modification according to home court advantage (0.3469).