| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 19-Nov-05 | vs St Peter's (138) | 82-71 | Won | -0.1376 | -0.0000 |
| 23-Nov-05 | vs Robert Morris PA (250) | 86-59 | Won | -0.9057 | -0.0000 |
| 26-Nov-05 | vs Maine (289) | 62-49 | Won | -1.1581 | -0.0000 |
| 29-Nov-05 | vs St Francis NY (285) | 79-58 | Won | -1.1190 | -0.0000 |
| 04-Dec-05 | vs Auburn (107) | 78-41 | Won | 0.0515 | -0.0000 |
| 07-Dec-05 | at Duquesne (317) | 71-60 | Won | -0.9509 | -0.0000 |
| 10-Dec-05 | vs Penn St (94) | 91-54 | Won | 0.1710 | -0.0000 |
| 17-Dec-05 | vs Vermont (237) | 63-52 | Won | -0.8148 | -0.0000 |
| 21-Dec-05 | vs Coppin St (279) | 77-51 | Won | -1.0870 | -0.0000 |
| 28-Dec-05 | at South Carolina (43) | 58-51 | Won | 1.3266 | 0.8621 |
| 31-Dec-05 | vs Wisconsin (37) | 73-64 | Won | 0.6846 | 0.2201 |
| 04-Jan-06 | vs Notre Dame (64) | 100-97 | Won | 0.4045 | -0.0000 |
| 12-Jan-06 | vs DePaul (79) | 73-65 | Won | 0.2883 | -0.0000 |
| 15-Jan-06 | at Louisville (52) | 61-57 | Won | 1.2331 | 0.7686 |
| 18-Jan-06 | at Rutgers (54) | 76-68 | Won | 1.1871 | 0.7226 |
| 21-Jan-06 | at St John's NY (119) | 50-55 | Lost | 0.6323 | -1.0000 |
| 23-Jan-06 | vs Syracuse (23) | 80-67 | Won | 0.8865 | 0.4220 |
| 28-Jan-06 | vs Marquette (36) | 77-71 | Won | 0.6985 | 0.2340 |
| 31-Jan-06 | at Connecticut (2) | 76-80 | Lost | 2.3673 | -0.0972 |
| 05-Feb-06 | at Georgetown DC (15) | 58-61 | Lost | 1.7389 | -0.7256 |
| 09-Feb-06 | vs West Virginia (24) | 57-53 | Won | 0.8724 | 0.4079 |
| 12-Feb-06 | vs Cincinnati (45) | 89-69 | Won | 0.6121 | 0.1476 |
| 15-Feb-06 | at Providence RI (93) | 85-77 | Won | 0.8734 | 0.4088 |
| 18-Feb-06 | at Marquette (36) | 82-84 | Lost | 1.3923 | -1.0000 |
| 25-Feb-06 | vs Providence RI (93) | 81-68 | Won | 0.1796 | -0.0000 |
| 27-Feb-06 | at West Virginia (24) | 62-67 | Lost | 1.5662 | -0.8983 |
| 03-Mar-06 | vs Seton Hall (59) | 61-65 | Lost | 0.4627 | -1.0000 |
| 08-Mar-06 | vs Louisville (52) | 61-56 | Won | 0.8862 | 0.4217 |
| 09-Mar-06 | at West Virginia (24) | 68-57 | Won | 1.2193 | 0.7548 |
| 10-Mar-06 | at Villanova (3) | 68-54 | Won | 1.8594 | 1.0000 |
| 11-Mar-06 | vs Syracuse (23) | 61-65 | Lost | 1.2334 | -1.0000 |
| 17-Mar-06 | vs Kent St (53) | 79-64 | Won | 0.8416 | 0.3771 |
| 19-Mar-06 | vs Bradley (38) | 66-72 | Lost | 1.0275 | -1.0000 |
A red opponent rating indicates modification according to home court advantage (0.3469).