| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 18-Nov-05 | vs Rice (220) | 82-65 | Won | -0.7051 | -0.0000 |
| 19-Nov-05 | vs Winthrop (84) | 64-71 | Lost | 0.2573 | -1.0000 |
| 23-Nov-05 | vs Eastern Washington (166) | 83-73 | Won | -0.0155 | -0.0000 |
| 25-Nov-05 | at Oral Roberts (142) | 73-70 | Won | 0.1613 | 0.1159 |
| 26-Nov-05 | vs South Carolina (43) | 92-89 | Won | 0.9798 | 0.9344 |
| 30-Nov-05 | at Nebraska (80) | 74-84 | Lost | 0.9782 | -1.0000 |
| 03-Dec-05 | vs South Dakota St (265) | 87-52 | Won | -1.0352 | -0.0000 |
| 07-Dec-05 | vs Valparaiso (194) | 69-54 | Won | -0.5545 | -0.0000 |
| 10-Dec-05 | at Wisconsin (37) | 63-77 | Lost | 1.3783 | -0.6671 |
| 17-Dec-05 | vs San Francisco (173) | 61-48 | Won | -0.4046 | -0.0000 |
| 19-Dec-05 | vs Oakland (261) | 90-69 | Won | -0.9975 | -0.0000 |
| 22-Dec-05 | vs Delaware St (151) | 60-48 | Won | -0.2342 | -0.0000 |
| 03-Jan-06 | vs Connecticut (2) | 94-79 | Won | 1.6735 | 1.0000 |
| 07-Jan-06 | vs Cincinnati (45) | 66-70 | Lost | 0.6121 | -1.0000 |
| 11-Jan-06 | at Seton Hall (59) | 67-63 | Won | 1.1565 | 1.0000 |
| 14-Jan-06 | at West Virginia (24) | 85-104 | Lost | 1.5662 | -0.4792 |
| 17-Jan-06 | at DePaul (79) | 82-79 | Won | 0.9821 | 0.9367 |
| 20-Jan-06 | vs Notre Dame (64) | 67-65 | Won | 0.4045 | 0.3591 |
| 25-Jan-06 | vs DePaul (79) | 62-47 | Won | 0.2883 | 0.2429 |
| 28-Jan-06 | at Pittsburgh (13) | 71-77 | Lost | 1.8114 | -0.2340 |
| 01-Feb-06 | vs St John's NY (119) | 81-61 | Won | -0.0615 | -0.0000 |
| 04-Feb-06 | at Villanova (3) | 67-72 | Lost | 2.2063 | 0.0000 |
| 12-Feb-06 | at Rutgers (54) | 84-91 | Lost | 1.1871 | -0.8583 |
| 16-Feb-06 | vs Georgetown DC (15) | 57-51 | Won | 1.0451 | 0.9997 |
| 18-Feb-06 | vs Pittsburgh (13) | 84-82 | Won | 1.1176 | 1.0000 |
| 25-Feb-06 | at Notre Dame (64) | 80-72 | Won | 1.0983 | 1.0000 |
| 01-Mar-06 | at Louisville (52) | 60-67 | Lost | 1.2331 | -0.8123 |
| 04-Mar-06 | vs Providence RI (93) | 88-78 | Won | 0.1796 | 0.1342 |
| 09-Mar-06 | vs Georgetown DC (15) | 59-62 | Lost | 1.3920 | -0.6534 |
| 16-Mar-06 | vs Alabama (48) | 85-90 | Lost | 0.9170 | -1.0000 |
A red opponent rating indicates modification according to home court advantage (0.3469).