| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 19-Nov-05 | at Jacksonville FL (333) | 78-48 | Won | -2.0073 | -0.0000 |
| 21-Nov-05 | vs Alcorn St (309) | 85-67 | Won | -1.5700 | -0.0000 |
| 25-Nov-05 | at Florida (4) | 66-74 | Lost | 2.1954 | 0.0000 |
| 29-Nov-05 | vs Purdue (148) | 97-57 | Won | -0.2250 | -0.0000 |
| 02-Dec-05 | vs Louisiana-Monroe (254) | 85-62 | Won | -0.9189 | -0.0000 |
| 07-Dec-05 | vs Texas Southern (326) | 90-59 | Won | -1.9216 | -0.0000 |
| 17-Dec-05 | vs Bowling Green (256) | 71-60 | Won | -0.5799 | -0.0000 |
| 20-Dec-05 | vs Stetson (298) | 75-57 | Won | -1.3298 | -0.0000 |
| 22-Dec-05 | vs Campbell (311) | 108-73 | Won | -1.5865 | -0.0000 |
| 31-Dec-05 | vs Nebraska (80) | 74-60 | Won | 0.6314 | 0.6918 |
| 04-Jan-06 | at Clemson (62) | 55-61 | Lost | 1.1101 | -0.8294 |
| 07-Jan-06 | vs Virginia Tech (117) | 74-68 | Won | -0.0367 | 0.0237 |
| 11-Jan-06 | at Virginia (75) | 87-82 | Won | 0.9989 | 1.0000 |
| 14-Jan-06 | at Boston College (19) | 87-90 | Lost | 1.7040 | -0.2356 |
| 22-Jan-06 | vs North Carolina (16) | 80-81 | Lost | 1.0317 | -0.9078 |
| 24-Jan-06 | at Wake Forest (77) | 75-68 | Won | 0.9892 | 1.0000 |
| 29-Jan-06 | vs Miami FL (67) | 78-84 | Lost | 0.3683 | -1.0000 |
| 01-Feb-06 | vs Clemson (62) | 69-59 | Won | 0.4163 | 0.4768 |
| 04-Feb-06 | at Duke (1) | 96-97 | Lost | 2.3873 | 0.0000 |
| 09-Feb-06 | vs Georgia Tech (124) | 80-79 | Won | -0.0898 | -0.0000 |
| 12-Feb-06 | vs Massachusetts (125) | 73-63 | Won | -0.0909 | -0.0000 |
| 15-Feb-06 | at North Carolina St (25) | 64-86 | Lost | 1.5475 | -0.3921 |
| 18-Feb-06 | vs Virginia (75) | 76-62 | Won | 0.3052 | 0.3656 |
| 22-Feb-06 | vs Maryland (55) | 71-60 | Won | 0.4883 | 0.5487 |
| 25-Feb-06 | at Virginia Tech (117) | 61-72 | Lost | 0.6570 | -1.0000 |
| 01-Mar-06 | vs Duke (1) | 79-74 | Won | 1.6935 | 1.0000 |
| 05-Mar-06 | at Miami FL (67) | 67-64 | Won | 1.0621 | 1.0000 |
| 09-Mar-06 | vs Wake Forest (77) | 66-78 | Lost | 0.6423 | -1.0000 |
| 17-Mar-06 | vs Butler (88) | 67-63 | Won | 0.2144 | 0.2749 |
| 21-Mar-06 | vs South Carolina (43) | 68-69 | Lost | 0.6329 | -1.0000 |
A red opponent rating indicates modification according to home court advantage (0.3469).