| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 19-Nov-05 | vs Gardner-Webb (214) | 83-80 | Won | -0.6968 | -0.0000 |
| 22-Nov-05 | vs Cleveland St (241) | 112-55 | Won | -0.8312 | -0.0000 |
| 25-Nov-05 | vs UC-Santa Barbara (192) | 83-66 | Won | -0.5334 | -0.0000 |
| 29-Nov-05 | vs Illinois (9) | 64-68 | Lost | 1.1917 | -1.0000 |
| 03-Dec-05 | at Kentucky (27) | 83-79 | Won | 1.5043 | 1.0000 |
| 07-Dec-05 | vs St Louis (106) | 75-63 | Won | 0.0676 | -0.0000 |
| 17-Dec-05 | vs Santa Clara (171) | 76-58 | Won | -0.3987 | -0.0000 |
| 21-Dec-05 | at Southern Cal (83) | 59-74 | Lost | 0.9569 | -1.0000 |
| 28-Dec-05 | vs UNC-Asheville (247) | 89-47 | Won | -0.8658 | -0.0000 |
| 03-Jan-06 | vs Davidson (118) | 82-58 | Won | -0.0464 | -0.0000 |
| 07-Jan-06 | vs North Carolina St (25) | 82-69 | Won | 0.8537 | 0.4751 |
| 10-Jan-06 | at Virginia Tech (117) | 64-61 | Won | 0.6570 | 0.2784 |
| 14-Jan-06 | vs Miami FL (67) | 70-81 | Lost | 0.3683 | -1.0000 |
| 19-Jan-06 | at Virginia (75) | 68-72 | Lost | 0.9989 | -1.0000 |
| 22-Jan-06 | at Florida St (47) | 81-80 | Won | 1.2864 | 0.9078 |
| 25-Jan-06 | vs Boston College (19) | 74-81 | Lost | 1.0102 | -1.0000 |
| 28-Jan-06 | vs Arizona (42) | 86-69 | Won | 0.6436 | 0.2650 |
| 02-Feb-06 | at Maryland (55) | 77-62 | Won | 1.1820 | 0.8034 |
| 04-Feb-06 | vs Clemson (62) | 76-61 | Won | 0.4163 | 0.0377 |
| 07-Feb-06 | vs Duke (1) | 83-87 | Lost | 1.6935 | -0.6851 |
| 12-Feb-06 | at Miami FL (67) | 80-70 | Won | 1.0621 | 0.6834 |
| 15-Feb-06 | vs Georgia Tech (124) | 82-75 | Won | -0.0898 | -0.0000 |
| 19-Feb-06 | at Wake Forest (77) | 83-72 | Won | 0.9892 | 0.6106 |
| 22-Feb-06 | at North Carolina St (25) | 95-71 | Won | 1.5475 | 1.0000 |
| 26-Feb-06 | vs Maryland (55) | 81-57 | Won | 0.4883 | 0.1096 |
| 01-Mar-06 | vs Virginia (75) | 99-54 | Won | 0.3052 | -0.0000 |
| 04-Mar-06 | at Duke (1) | 83-76 | Won | 2.3873 | 1.0000 |
| 10-Mar-06 | vs Virginia (75) | 79-67 | Won | 0.6520 | 0.2734 |
| 11-Mar-06 | vs Boston College (19) | 82-85 | Lost | 1.3571 | -1.0000 |
| 17-Mar-06 | vs Murray St (76) | 69-65 | Won | 0.6438 | 0.2652 |
| 19-Mar-06 | vs George Mason (20) | 60-65 | Lost | 1.2827 | -1.0000 |
A red opponent rating indicates modification according to home court advantage (0.3469).