| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 18-Nov-05 | vs Fairleigh Dickinson (169) | 111-85 | Won | -0.3855 | -0.0000 |
| 21-Nov-05 | vs Gonzaga (12) | 76-88 | Lost | 1.4761 | -0.3590 |
| 23-Nov-05 | vs Arkansas (28) | 75-62 | Won | 1.1382 | 1.0000 |
| 27-Nov-05 | vs Nicholls St (283) | 88-56 | Won | -1.1058 | -0.0000 |
| 30-Nov-05 | vs Minnesota (70) | 83-66 | Won | 0.3297 | 0.4946 |
| 05-Dec-05 | at George Washington (8) | 70-78 | Lost | 1.5710 | -0.2642 |
| 07-Dec-05 | vs Western Carolina (233) | 87-57 | Won | -0.7815 | -0.0000 |
| 11-Dec-05 | vs Boston College (19) | 73-71 | Won | 1.0102 | 1.0000 |
| 23-Dec-05 | vs American U. (239) | 81-55 | Won | -0.8254 | -0.0000 |
| 28-Dec-05 | vs Delaware St (151) | 68-54 | Won | -0.2342 | -0.0000 |
| 31-Dec-05 | vs VMI (315) | 99-68 | Won | -1.6220 | -0.0000 |
| 04-Jan-06 | vs TAMU-Corpus Christi (184) | 99-73 | Won | -0.4732 | -0.0000 |
| 07-Jan-06 | at Miami FL (67) | 70-84 | Lost | 1.0621 | -0.7731 |
| 11-Jan-06 | at Duke (1) | 52-76 | Lost | 2.3873 | 0.0000 |
| 15-Jan-06 | vs Wake Forest (77) | 90-86 | Won | 0.2954 | 0.4603 |
| 21-Jan-06 | vs Virginia Tech (117) | 81-72 | Won | -0.0367 | 0.1281 |
| 25-Jan-06 | at Georgia Tech (124) | 86-74 | Won | 0.6040 | 0.7688 |
| 28-Jan-06 | at Temple (78) | 85-91 | Lost | 0.9885 | -0.8467 |
| 02-Feb-06 | vs North Carolina (16) | 62-77 | Lost | 1.0317 | -0.8034 |
| 05-Feb-06 | at North Carolina St (25) | 58-62 | Lost | 1.5475 | -0.2877 |
| 07-Feb-06 | vs Virginia (75) | 76-65 | Won | 0.3052 | 0.4700 |
| 11-Feb-06 | vs Duke (1) | 88-96 | Lost | 1.6935 | -0.1416 |
| 14-Feb-06 | at Clemson (62) | 77-89 | Lost | 1.1101 | -0.7251 |
| 18-Feb-06 | vs Georgia Tech (124) | 87-84 | Won | -0.0898 | 0.0751 |
| 22-Feb-06 | at Florida St (47) | 60-71 | Lost | 1.2864 | -0.5487 |
| 26-Feb-06 | at North Carolina (16) | 57-81 | Lost | 1.7255 | -0.1096 |
| 01-Mar-06 | vs Miami FL (67) | 65-61 | Won | 0.3683 | 0.5332 |
| 05-Mar-06 | at Virginia (75) | 71-70 | Won | 0.9989 | 1.0000 |
| 09-Mar-06 | vs Georgia Tech (124) | 82-64 | Won | 0.2571 | 0.4219 |
| 10-Mar-06 | at Boston College (19) | 66-80 | Lost | 1.3571 | -0.4781 |
| 18-Mar-06 | vs Manhattan (81) | 84-87 | Lost | 0.2750 | -1.0000 |
A red opponent rating indicates modification according to home court advantage (0.3469).