| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 10-Nov-05 | vs Mississippi Valley St (313) | 78-64 | Won | -1.6090 | -0.0000 |
| 11-Nov-05 | vs George Mason (20) | 83-78 | Won | 0.9359 | 1.0000 |
| 17-Nov-05 | vs Florida (4) | 72-77 | Lost | 1.8485 | 0.0000 |
| 18-Nov-05 | vs Texas Tech (112) | 78-73 | Won | 0.3674 | 0.7252 |
| 21-Nov-05 | vs UNC-Asheville (247) | 79-63 | Won | -0.8658 | -0.0000 |
| 25-Nov-05 | vs Appalachian St (225) | 91-78 | Won | -0.7317 | -0.0000 |
| 29-Nov-05 | vs Wisconsin (37) | 91-88 | Won | 0.6846 | 1.0000 |
| 03-Dec-05 | at Elon (178) | 78-59 | Won | -0.1024 | 0.2553 |
| 13-Dec-05 | vs DePaul (79) | 81-84 | Lost | 0.2883 | -1.0000 |
| 17-Dec-05 | vs Princeton (219) | 61-42 | Won | -0.7049 | -0.0000 |
| 22-Dec-05 | at Richmond (176) | 47-40 | Won | 0.2542 | 0.6119 |
| 30-Dec-05 | vs Charleston Southern (227) | 87-47 | Won | -0.7539 | -0.0000 |
| 03-Jan-06 | vs East Carolina (300) | 58-54 | Won | -1.3656 | -0.0000 |
| 08-Jan-06 | vs Duke (1) | 64-82 | Lost | 1.6935 | 0.0000 |
| 11-Jan-06 | at Clemson (62) | 73-74 | Lost | 1.1101 | -0.5322 |
| 15-Jan-06 | at Maryland (55) | 86-90 | Lost | 1.1820 | -0.4603 |
| 18-Jan-06 | vs Georgia Tech (124) | 86-71 | Won | -0.0898 | 0.2679 |
| 21-Jan-06 | at North Carolina St (25) | 82-92 | Lost | 1.5475 | -0.0948 |
| 24-Jan-06 | vs Florida St (47) | 68-75 | Lost | 0.5926 | -1.0000 |
| 28-Jan-06 | vs Virginia Tech (117) | 70-76 | Lost | -0.0367 | -1.0000 |
| 31-Jan-06 | at Miami FL (67) | 69-78 | Lost | 1.0621 | -0.5802 |
| 04-Feb-06 | at Virginia (75) | 73-75 | Lost | 0.9989 | -0.6434 |
| 08-Feb-06 | vs Boston College (19) | 66-72 | Lost | 1.0102 | -0.6321 |
| 11-Feb-06 | vs Charlotte (91) | 59-56 | Won | 0.1917 | 0.5494 |
| 14-Feb-06 | at Duke (1) | 70-93 | Lost | 2.3873 | 0.0000 |
| 19-Feb-06 | vs North Carolina (16) | 72-83 | Lost | 1.0317 | -0.6106 |
| 22-Feb-06 | vs Clemson (62) | 74-68 | Won | 0.4163 | 0.7740 |
| 25-Feb-06 | at Georgia Tech (124) | 61-76 | Lost | 0.6040 | -1.0000 |
| 28-Feb-06 | at Boston College (19) | 65-80 | Lost | 1.7040 | 0.0000 |
| 04-Mar-06 | vs North Carolina St (25) | 76-63 | Won | 0.8537 | 1.0000 |
| 09-Mar-06 | at Florida St (47) | 78-66 | Won | 0.9395 | 1.0000 |
| 10-Mar-06 | at North Carolina St (25) | 82-71 | Won | 1.2006 | 1.0000 |
| 11-Mar-06 | at Duke (1) | 66-78 | Lost | 2.0404 | 0.0000 |
| 15-Mar-06 | at Minnesota (70) | 58-73 | Lost | 1.0235 | -0.6188 |
A red opponent rating indicates modification according to home court advantage (0.3469).