| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 10-Nov-05 | vs San José St (266) | 88-54 | Won | -1.0357 | -0.0000 |
| 11-Nov-05 | vs Georgia Southern (135) | 74-61 | Won | -0.1198 | 0.5127 |
| 17-Nov-05 | vs Syracuse (23) | 46-81 | Lost | 1.2334 | -0.1341 |
| 18-Nov-05 | at Wake Forest (77) | 73-78 | Lost | 0.6423 | -0.7252 |
| 23-Nov-05 | vs Furman (215) | 83-74 | Won | -0.6979 | -0.0000 |
| 26-Nov-05 | vs Morehead St (323) | 76-42 | Won | -1.8077 | -0.0000 |
| 30-Nov-05 | vs TCU (263) | 81-54 | Won | -1.0270 | -0.0000 |
| 03-Dec-05 | at San Francisco (173) | 72-90 | Lost | 0.2892 | -1.0000 |
| 07-Dec-05 | vs Louisiana Tech (96) | 53-68 | Lost | 0.1528 | -1.0000 |
| 10-Dec-05 | vs Texas-Pan American (328) | 103-50 | Won | -1.9781 | -0.0000 |
| 17-Dec-05 | at UNLV (108) | 73-84 | Lost | 0.7394 | -0.6281 |
| 21-Dec-05 | vs Arkansas (28) | 65-78 | Lost | 1.1382 | -0.2293 |
| 29-Dec-05 | at New Mexico St (123) | 69-63 | Won | 0.6089 | 1.0000 |
| 01-Jan-06 | vs UTEP (98) | 61-60 | Won | 0.1456 | 0.7782 |
| 07-Jan-06 | at Texas A&M (40) | 55-63 | Lost | 1.3506 | -0.0169 |
| 11-Jan-06 | vs Baylor (146) | 79-61 | Won | -0.2089 | 0.4237 |
| 14-Jan-06 | vs Iowa St (99) | 76-73 | Won | 0.1388 | 0.7714 |
| 17-Jan-06 | at Texas (10) | 46-80 | Lost | 1.8840 | 0.0000 |
| 21-Jan-06 | at Oklahoma (46) | 48-60 | Lost | 1.3002 | -0.0673 |
| 28-Jan-06 | vs Oklahoma St (102) | 92-90 | Won | 0.1340 | 0.7665 |
| 30-Jan-06 | at Kansas (21) | 52-86 | Lost | 1.6126 | 0.0000 |
| 04-Feb-06 | vs Missouri (144) | 73-55 | Won | -0.2048 | 0.4277 |
| 06-Feb-06 | vs Texas (10) | 44-65 | Lost | 1.1902 | -0.1772 |
| 11-Feb-06 | at Colorado (63) | 64-66 | Lost | 1.1022 | -0.2652 |
| 15-Feb-06 | vs Kansas St (122) | 70-56 | Won | -0.0743 | 0.5582 |
| 18-Feb-06 | at Nebraska (80) | 70-64 | Won | 0.9782 | 1.0000 |
| 20-Feb-06 | vs Oklahoma (46) | 70-71 | Lost | 0.6064 | -0.7611 |
| 25-Feb-06 | at Oklahoma St (102) | 63-74 | Lost | 0.8277 | -0.5397 |
| 01-Mar-06 | at Baylor (146) | 66-77 | Lost | 0.4849 | -0.8826 |
| 04-Mar-06 | vs Texas A&M (40) | 59-75 | Lost | 0.6568 | -0.7106 |
| 09-Mar-06 | vs Kansas St (122) | 73-65 | Won | 0.2725 | 0.9051 |
| 10-Mar-06 | at Texas (10) | 70-77 | Lost | 1.5371 | 0.0000 |
A red opponent rating indicates modification according to home court advantage (0.3469).