| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 23-Nov-05 | vs Portland St (222) | 72-64 | Won | -0.7104 | -0.0000 |
| 25-Nov-05 | vs Howard (316) | 96-62 | Won | -1.6387 | -0.0000 |
| 26-Nov-05 | vs Iona (51) | 72-89 | Lost | 0.5463 | -0.9394 |
| 29-Nov-05 | vs Northern Iowa (41) | 68-61 | Won | 0.6532 | 1.0000 |
| 03-Dec-05 | vs Fresno St (130) | 77-84 | Lost | -0.0996 | -1.0000 |
| 05-Dec-05 | at Drake (162) | 89-74 | Won | 0.3520 | 0.8663 |
| 09-Dec-05 | vs Iowa (17) | 72-60 | Won | 1.0314 | 1.0000 |
| 17-Dec-05 | vs Ohio State (11) | 67-70 | Lost | 1.5031 | 0.0000 |
| 21-Dec-05 | at South Florida (230) | 83-74 | Won | -0.4288 | 0.0855 |
| 22-Dec-05 | at Northwestern St (66) | 81-77 | Won | 0.7316 | 1.0000 |
| 23-Dec-05 | vs Colorado St (155) | 87-80 | Won | 0.0599 | 0.5742 |
| 28-Dec-05 | vs Tennessee St (202) | 59-51 | Won | -0.5983 | -0.0000 |
| 07-Jan-06 | vs Kansas St (122) | 72-70 | Won | -0.0743 | 0.4399 |
| 09-Jan-06 | vs Texas (10) | 58-78 | Lost | 1.1902 | -0.2955 |
| 14-Jan-06 | at Texas Tech (112) | 73-76 | Lost | 0.7143 | -0.7714 |
| 17-Jan-06 | at Nebraska (80) | 88-75 | Won | 0.9782 | 1.0000 |
| 21-Jan-06 | vs Texas A&M (40) | 81-86 | Lost | 0.6568 | -0.8289 |
| 25-Jan-06 | at Missouri (144) | 82-58 | Won | 0.4890 | 1.0000 |
| 28-Jan-06 | vs Kansas (21) | 85-95 | Lost | 0.9188 | -0.5669 |
| 05-Feb-06 | vs Colorado (63) | 96-79 | Won | 0.4084 | 0.9227 |
| 08-Feb-06 | at Kansas St (122) | 63-66 | Lost | 0.6194 | -0.8663 |
| 11-Feb-06 | at Kansas (21) | 75-88 | Lost | 1.6126 | 0.0000 |
| 15-Feb-06 | vs Nebraska (80) | 63-73 | Lost | 0.2845 | -1.0000 |
| 18-Feb-06 | at Oklahoma (46) | 82-83 | Lost | 1.3002 | -0.1856 |
| 22-Feb-06 | vs Oklahoma St (102) | 68-52 | Won | 0.1340 | 0.6482 |
| 25-Feb-06 | at Baylor (146) | 73-91 | Lost | 0.4849 | -1.0000 |
| 28-Feb-06 | vs Missouri (144) | 85-78 | Won | -0.2048 | 0.3094 |
| 04-Mar-06 | at Colorado (63) | 82-84 | Lost | 1.1022 | -0.3835 |
| 09-Mar-06 | at Oklahoma St (102) | 70-79 | Lost | 0.4808 | -1.0000 |
A red opponent rating indicates modification according to home court advantage (0.3469).