| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 18-Nov-05 | vs Dartmouth (307) | 80-61 | Won | -1.5356 | -0.0000 |
| 22-Nov-05 | vs Buffalo (116) | 92-63 | Won | -0.0340 | -0.0000 |
| 25-Nov-05 | vs Drake (162) | 87-84 | Won | 0.0051 | -0.0000 |
| 26-Nov-05 | at Oklahoma St (102) | 76-68 | Won | 0.4808 | 0.1238 |
| 03-Dec-05 | vs Sacred Heart (281) | 77-66 | Won | -1.1014 | -0.0000 |
| 06-Dec-05 | at Michigan St (30) | 70-77 | Lost | 1.1126 | -1.0000 |
| 11-Dec-05 | at Maryland (55) | 71-73 | Lost | 1.1820 | -1.0000 |
| 18-Dec-05 | vs Texas Southern (326) | 80-53 | Won | -1.9216 | -0.0000 |
| 22-Dec-05 | vs Harvard (253) | 89-55 | Won | -0.9119 | -0.0000 |
| 27-Dec-05 | at Duquesne (317) | 81-69 | Won | -0.9509 | -0.0000 |
| 31-Dec-05 | at Rhode Island (141) | 78-56 | Won | 0.5208 | 0.1637 |
| 03-Jan-06 | vs Massachusetts (125) | 91-62 | Won | -0.0909 | -0.0000 |
| 08-Jan-06 | at Georgia Tech (124) | 58-60 | Lost | 0.6040 | -1.0000 |
| 10-Jan-06 | vs North Carolina St (25) | 60-78 | Lost | 0.8537 | -1.0000 |
| 14-Jan-06 | vs Florida St (47) | 90-87 | Won | 0.5926 | 0.2356 |
| 17-Jan-06 | at Holy Cross (126) | 63-53 | Won | 0.6016 | 0.2445 |
| 21-Jan-06 | at Miami FL (67) | 65-61 | Won | 1.0621 | 0.7050 |
| 25-Jan-06 | at North Carolina (16) | 81-74 | Won | 1.7255 | 1.0000 |
| 29-Jan-06 | vs Georgia Tech (124) | 66-64 | Won | -0.0898 | -0.0000 |
| 01-Feb-06 | vs Duke (1) | 81-83 | Lost | 1.6935 | -0.6636 |
| 04-Feb-06 | at Virginia Tech (117) | 74-73 | Won | 0.6570 | 0.2999 |
| 08-Feb-06 | at Wake Forest (77) | 72-66 | Won | 0.9892 | 0.6321 |
| 11-Feb-06 | vs Clemson (62) | 67-61 | Won | 0.4163 | 0.0592 |
| 13-Feb-06 | vs Stony Brook (319) | 59-47 | Won | -1.7471 | -0.0000 |
| 16-Feb-06 | vs Miami FL (67) | 65-54 | Won | 0.3683 | 0.0112 |
| 21-Feb-06 | at Virginia (75) | 58-72 | Lost | 0.9989 | -1.0000 |
| 25-Feb-06 | at North Carolina St (25) | 74-72 | Won | 1.5475 | 1.0000 |
| 28-Feb-06 | vs Wake Forest (77) | 80-65 | Won | 0.2954 | -0.0000 |
| 04-Mar-06 | vs Virginia Tech (117) | 59-57 | Won | -0.0367 | -0.0000 |
| 10-Mar-06 | vs Maryland (55) | 80-66 | Won | 0.8351 | 0.4781 |
| 11-Mar-06 | at North Carolina (16) | 85-82 | Won | 1.3786 | 1.0000 |
| 12-Mar-06 | at Duke (1) | 76-78 | Lost | 2.0404 | -0.3167 |
| 16-Mar-06 | vs Pacific CA (89) | 88-76 | Won | 0.5527 | 0.1956 |
| 18-Mar-06 | vs Montana (68) | 69-56 | Won | 0.7104 | 0.3533 |
| 24-Mar-06 | at Villanova (3) | 59-60 | Lost | 1.8594 | -0.4977 |
A red opponent rating indicates modification according to home court advantage (0.3469).