| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 18-Nov-05 | vs South Dakota St (265) | 90-65 | Won | -1.0352 | -0.0000 |
| 20-Nov-05 | vs Texas-Pan American (328) | 71-59 | Won | -1.9781 | -0.0000 |
| 22-Nov-05 | vs Texas Southern (326) | 93-59 | Won | -1.9216 | -0.0000 |
| 25-Nov-05 | vs Wichita St (31) | 55-54 | Won | 1.1000 | 0.5614 |
| 26-Nov-05 | vs Rutgers (54) | 77-57 | Won | 0.8402 | 0.3016 |
| 29-Nov-05 | at North Carolina (16) | 68-64 | Won | 1.7255 | 1.0000 |
| 03-Dec-05 | vs Xavier OH (71) | 65-62 | Won | 0.6744 | 0.1359 |
| 05-Dec-05 | vs Arkansas-Little Rock (200) | 75-49 | Won | -0.5959 | -0.0000 |
| 08-Dec-05 | vs Georgetown DC (15) | 58-48 | Won | 1.0451 | 0.5066 |
| 10-Dec-05 | at Oregon (111) | 89-59 | Won | 0.3695 | -0.0000 |
| 18-Dec-05 | vs Coppin St (279) | 61-42 | Won | -1.0870 | -0.0000 |
| 21-Dec-05 | vs Missouri (144) | 82-50 | Won | 0.1421 | -0.0000 |
| 28-Dec-05 | vs SE Missouri St (312) | 89-64 | Won | -1.5933 | -0.0000 |
| 30-Dec-05 | vs Tennessee-Martin (207) | 84-46 | Won | -0.6543 | -0.0000 |
| 05-Jan-06 | vs Michigan St (30) | 60-50 | Won | 0.7657 | 0.2272 |
| 07-Jan-06 | at Iowa (17) | 48-63 | Lost | 1.7251 | -0.8134 |
| 14-Jan-06 | vs Michigan (33) | 79-74 | Won | 0.7141 | 0.1756 |
| 17-Jan-06 | at Indiana (29) | 60-62 | Lost | 1.4808 | -1.0000 |
| 21-Jan-06 | at Northwestern (86) | 58-47 | Won | 0.9155 | 0.3770 |
| 25-Jan-06 | vs Minnesota (70) | 77-53 | Won | 0.3297 | -0.0000 |
| 28-Jan-06 | vs Purdue (148) | 76-58 | Won | -0.2250 | -0.0000 |
| 31-Jan-06 | at Wisconsin (37) | 66-51 | Won | 1.3783 | 0.8398 |
| 04-Feb-06 | vs Penn St (94) | 65-66 | Lost | 0.1710 | -1.0000 |
| 12-Feb-06 | at Ohio State (11) | 53-69 | Lost | 1.8499 | -0.6886 |
| 15-Feb-06 | vs Northwestern (86) | 63-47 | Won | 0.2218 | -0.0000 |
| 19-Feb-06 | vs Indiana (29) | 70-58 | Won | 0.7870 | 0.2485 |
| 21-Feb-06 | at Michigan (33) | 64-72 | Lost | 1.4079 | -1.0000 |
| 25-Feb-06 | vs Iowa (17) | 71-59 | Won | 1.0314 | 0.4928 |
| 28-Feb-06 | at Minnesota (70) | 71-65 | Won | 1.0235 | 0.4850 |
| 04-Mar-06 | at Michigan St (30) | 75-68 | Won | 1.4595 | 0.9209 |
| 10-Mar-06 | vs Michigan St (30) | 56-61 | Lost | 1.1126 | -1.0000 |
| 16-Mar-06 | vs Air Force (60) | 78-69 | Won | 0.7956 | 0.2571 |
| 18-Mar-06 | vs Washington (18) | 64-67 | Lost | 1.3740 | -1.0000 |
A red opponent rating indicates modification according to home court advantage (0.3469).