| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 13-Nov-05 | at Lehigh (172) | 61-59 | Won | -0.0534 | 0.3780 |
| 14-Nov-05 | at Charlotte (91) | 61-47 | Won | 0.5386 | 0.9700 |
| 15-Nov-05 | vs UNC-Wilmington (34) | 48-56 | Lost | 1.0576 | -0.5110 |
| 21-Nov-05 | vs Florida Atlantic (264) | 69-59 | Won | -1.0326 | -0.0000 |
| 26-Nov-05 | at DePaul (79) | 49-59 | Lost | 0.9821 | -0.5866 |
| 30-Nov-05 | at Virginia (75) | 57-72 | Lost | 0.9989 | -0.5697 |
| 03-Dec-05 | vs Delaware St (151) | 61-54 | Won | -0.2342 | 0.1972 |
| 14-Dec-05 | vs Illinois-Chicago (129) | 62-71 | Lost | -0.0983 | -1.0000 |
| 18-Dec-05 | at Seton Hall (59) | 44-42 | Won | 1.1565 | 1.0000 |
| 01-Jan-06 | vs Northern Colorado (322) | 82-47 | Won | -1.7607 | -0.0000 |
| 04-Jan-06 | vs Purdue (148) | 66-53 | Won | -0.2250 | 0.2063 |
| 07-Jan-06 | at Minnesota (70) | 57-49 | Won | 1.0235 | 1.0000 |
| 11-Jan-06 | vs Penn St (94) | 61-65 | Lost | 0.1710 | -1.0000 |
| 14-Jan-06 | at Wisconsin (37) | 52-68 | Lost | 1.3783 | -0.1903 |
| 18-Jan-06 | at Michigan (33) | 51-68 | Lost | 1.4079 | -0.1607 |
| 21-Jan-06 | vs Illinois (9) | 47-58 | Lost | 1.1917 | -0.3770 |
| 25-Jan-06 | at Purdue (148) | 78-76 | Won | 0.4687 | 0.9001 |
| 01-Feb-06 | at Indiana (29) | 63-72 | Lost | 1.4808 | -0.0878 |
| 04-Feb-06 | vs Michigan St (30) | 66-77 | Lost | 0.7657 | -0.8030 |
| 08-Feb-06 | vs Iowa (17) | 51-48 | Won | 1.0314 | 1.0000 |
| 11-Feb-06 | vs IPFW (275) | 73-49 | Won | -1.0772 | -0.0000 |
| 15-Feb-06 | at Illinois (9) | 47-63 | Lost | 1.8854 | 0.0000 |
| 18-Feb-06 | at Ohio State (11) | 52-61 | Lost | 1.8499 | 0.0000 |
| 23-Feb-06 | vs Wisconsin (37) | 62-51 | Won | 0.6846 | 1.0000 |
| 25-Feb-06 | at Penn St (94) | 55-68 | Lost | 0.8648 | -0.7039 |
| 01-Mar-06 | vs Ohio State (11) | 53-56 | Lost | 1.1562 | -0.4125 |
| 04-Mar-06 | vs Minnesota (70) | 57-53 | Won | 0.3297 | 0.7611 |
| 09-Mar-06 | at Penn St (94) | 42-60 | Lost | 0.5179 | -1.0000 |
A red opponent rating indicates modification according to home court advantage (0.3469).