| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 03-Sep-05 | vs South Florida (43) | 23-13 | Won | 0.2363 | -0.0000 |
| 10-Sep-05 | vs Cincinnati (82) | 42-24 | Won | -0.5816 | -0.0000 |
| 17-Sep-05 | vs Central Michigan (60) | 40-3 | Won | -0.1554 | -0.0000 |
| 24-Sep-05 | at Northwestern (15) | 34-29 | Won | 1.4361 | 0.2847 |
| 01-Oct-05 | vs Minnesota (18) | 44-14 | Won | 1.0026 | -0.0000 |
| 08-Oct-05 | vs Ohio State (4) | 17-10 | Won | 1.8592 | 0.7079 |
| 15-Oct-05 | at Michigan (12) | 25-27 | Lost | 1.5040 | -1.0000 |
| 22-Oct-05 | at Illinois (66) | 63-10 | Won | 0.0018 | -0.0000 |
| 29-Oct-05 | vs Purdue (34) | 33-15 | Won | 0.5219 | -0.0000 |
| 05-Nov-05 | vs Wisconsin (10) | 35-14 | Won | 1.2683 | 0.1169 |
| 19-Nov-05 | at Michigan St (37) | 31-22 | Won | 0.7215 | -0.0000 |
A red opponent rating indicates modification according to home field advantage (0.1322).