| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 03-Sep-05 | vs Rutgers (55) | 33-30 | Won | -0.0243 | 1.0000 |
| 10-Sep-05 | vs San José St (110) | 40-19 | Won | -1.6438 | -0.0000 |
| 17-Sep-05 | at California (31) | 20-35 | Lost | 0.8601 | -0.0095 |
| 24-Sep-05 | vs Michigan St (37) | 14-61 | Lost | 0.4571 | -0.4125 |
| 01-Oct-05 | at Iowa (21) | 7-35 | Lost | 1.2327 | 0.0000 |
| 08-Oct-05 | at Indiana (47) | 13-36 | Lost | 0.3641 | -0.5055 |
| 22-Oct-05 | vs Penn State (3) | 10-63 | Lost | 2.0191 | 0.0000 |
| 29-Oct-05 | vs Wisconsin (10) | 24-41 | Lost | 1.2683 | 0.0000 |
| 05-Nov-05 | at Ohio State (4) | 2-40 | Lost | 2.1236 | 0.0000 |
| 12-Nov-05 | at Purdue (34) | 3-37 | Lost | 0.7863 | -0.0832 |
| 19-Nov-05 | vs Northwestern (15) | 21-38 | Lost | 1.1717 | 0.0000 |
A red opponent rating indicates modification according to home field advantage (0.1322).