| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 03-Sep-05 | at Illinois (66) | 30-33 | Lost | 0.0018 | -1.0000 |
| 17-Sep-05 | at Buffalo (115) | 17-3 | Won | -1.8855 | -0.0000 |
| 30-Sep-05 | vs Pittsburgh (63) | 37-29 | Won | -0.1944 | 0.6976 |
| 08-Oct-05 | vs West Virginia (17) | 14-27 | Lost | 1.0880 | -0.0199 |
| 15-Oct-05 | at Syracuse (105) | 31-9 | Won | -1.1999 | -0.0000 |
| 22-Oct-05 | at Connecticut (81) | 26-24 | Won | -0.3060 | 0.5861 |
| 29-Oct-05 | vs Navy (68) | 31-21 | Won | -0.3396 | 0.5524 |
| 05-Nov-05 | vs South Florida (43) | 31-45 | Lost | 0.2363 | -0.8717 |
| 11-Nov-05 | at Louisville (30) | 5-56 | Lost | 0.8621 | -0.2458 |
| 26-Nov-05 | vs Cincinnati (82) | 44-9 | Won | -0.5816 | 0.3105 |
A red opponent rating indicates modification according to home field advantage (0.1322).