| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 10-Sep-05 | vs Akron (78) | 49-24 | Won | -0.5027 | -0.0000 |
| 17-Sep-05 | at Arizona (73) | 31-24 | Won | -0.1358 | 0.2101 |
| 24-Sep-05 | at Minnesota (18) | 35-42 | Lost | 1.2671 | -0.3870 |
| 01-Oct-05 | vs Notre Dame (6) | 28-49 | Lost | 1.5852 | -0.0689 |
| 08-Oct-05 | vs Iowa (21) | 17-34 | Lost | 0.9682 | -0.6859 |
| 15-Oct-05 | vs Northwestern (15) | 29-34 | Lost | 1.1717 | -0.4824 |
| 22-Oct-05 | at Wisconsin (10) | 20-31 | Lost | 1.5327 | -0.1214 |
| 29-Oct-05 | at Penn State (3) | 15-33 | Lost | 2.2836 | 0.0000 |
| 05-Nov-05 | vs Michigan St (37) | 28-21 | Won | 0.4571 | 0.8030 |
| 12-Nov-05 | vs Illinois (66) | 37-3 | Won | -0.2626 | 0.0832 |
| 19-Nov-05 | at Indiana (47) | 41-14 | Won | 0.3641 | 0.7100 |
A red opponent rating indicates modification according to home field advantage (0.1322).