| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 10-Sep-05 | at Purdue (34) | 24-49 | Lost | 0.7863 | 0.0000 |
| 17-Sep-05 | at Middle Tennessee St (109) | 17-7 | Won | -1.3738 | -0.0000 |
| 24-Sep-05 | vs Northern Illinois (56) | 48-42 | Won | -0.0298 | 1.0000 |
| 01-Oct-05 | vs Central Michigan (60) | 17-31 | Lost | -0.1554 | -0.7849 |
| 08-Oct-05 | at Buffalo (115) | 13-7 | Won | -1.8855 | -0.0000 |
| 15-Oct-05 | at Miami OH (71) | 23-51 | Lost | -0.1144 | -0.7439 |
| 22-Oct-05 | vs Army (91) | 0-20 | Lost | -0.7648 | -1.0000 |
| 29-Oct-05 | at Bowling Green (85) | 24-14 | Won | -0.3913 | 0.9792 |
| 05-Nov-05 | at Ball St (80) | 17-23 | Lost | -0.2813 | -0.9108 |
| 15-Nov-05 | vs Ohio U. (93) | 27-3 | Won | -0.9384 | 0.4321 |
| 24-Nov-05 | vs Kent St (119) | 35-3 | Won | -3.1276 | -0.0000 |
| 01-Dec-05 | vs Northern Illinois (56) | 31-30 | Won | -0.0298 | 1.0000 |
A red opponent rating indicates modification according to home field advantage (0.1322).